ai flashcards for cmm

exam 1

What is the main function of collagen in connective tissue?

Provides tensile strength and structural support.

Which type of collagen is most abundant and where is it found?

Type I collagen; found in bone

Which type of collagen is found in cartilage?

Type II collagen; forms cartilage and vitreous body.

Which type of collagen is found in reticular fibers?

Type III collagen; supports organs

Which type of collagen forms basement membranes?

Type IV collagen; forms meshwork in basal lamina.

Which type of collagen is found in anchoring fibrils beneath basal lamina?

Type VII collagen; anchors basal lamina to underlying connective tissue.

What is elastin and what is its function?

A stretchy connective tissue protein that provides elasticity and recoil in tissues such as lungs

What is fibrillin and what is its role?

A glycoprotein that forms microfibrils

What is fibrin and how is it formed?

A fibrous protein formed from fibrinogen by thrombin during blood clotting; stabilizes blood clots.

What is the relationship between elastin and fibrillin?

Elastin provides elasticity

Which connective tissue protein is defective in Ehlers-Danlos syndrome?

Collagen (commonly Type III).

Which connective tissue protein is defective in Alport syndrome?

Type IV collagen (affects basement membranes