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60-40-20 Rule of body weight
60% is water, 40% is intracellular fluid, 20% is extracellular fluid.
Intracellular fluid (ICF) compartment
The fluid compartment contained entirely within the cells.
Extracellular fluid (ECF) compartment
All body fluid located outside of the cells.
Two sub-compartments of extracellular fluid (ECF)
Interstitial fluid and intravascular fluid.
Pediatric body weight water percentage
75% to 80% of body weight.
Why older adults are prone to dehydration
Decreased total body water, decreased renal function, and diminished thirst perception.
Isotonic solution
A solution with the same solute concentration as blood.
Hypertonic solution effect on cells
It causes water to move out of cells, making them shrink.
Hypotonic solution effect on cells
It causes fluid to move into cells, potentially making them burst.
Filtration
Fluid movement through a membrane caused by hydrostatic pressure differences.
Hydrostatic pressure
The water-pushing force that pushes water outward from a confined space.
Diffusion
Free movement of particles from an area of higher to lower concentration.
Minimum daily urine output for toxic waste excretion
400 to 600 mL per day.
Antidiuretic hormone (ADH) primary function
Tells the kidneys to reabsorb water and sodium, slowing down urination.
Stimulants for ADH release
Low sodium, decreased blood volume, or increased body fluid osmolarity.
Renin secretion trigger
Sensed low blood volume or perfusion pressure by the kidneys.
ACE inhibitors mechanism of action
Block angiotensin II production, causing vasodilation and increased water excretion.
Fluid volume change of 1 pound of body weight
Approximately 500 mL of fluid.
Normal serum sodium level
136 to 145 mmol/L.
Normal serum potassium level
3.5 to 5.0 mEq/L.
Normal serum calcium level
9.0 to 10.5 mg/dL.
Normal serum phosphorus level
3.0 to 4.5 mg/dL.
Normal serum magnesium level
1.3 to 2.1 mg/dL.
Relationship between calcium and phosphorus levels
They exist in a balanced reciprocal relationship.
Hormone that increases blood calcium concentration
Parathyroid Hormone (PTH).
Hormone that deposits calcium into bones
Calcitonin.
Primary function of magnesium in muscles
Keeps law and order by regulating nerve function and muscle contraction.
Lactated Ringer's (LR) components
Normal saline with potassium, calcium, and lactate.
Primary risk of excessive Lactated Ringer's administration
Fluid and sodium overload leading to peripheral or pulmonary edema.
D5W tonicity behavior
Isotonic in the bag, but becomes hypotonic once dextrose is metabolized.
Why D5W should not be used for resuscitation
It can cause hyperglycemia.
0.9% Sodium Chloride (Normal Saline) primary uses
Shock, hyponatremia, blood transfusions, resuscitation, and fluid challenges.
0.45% Sodium Chloride (Half-Normal Saline) classification
Hypotonic solution used for water replacement and maintenance.
Contraindications for 0.45% Sodium Chloride
Patients with liver disease, trauma, or burns.
Clinical indication for Dextrose 5% in half-normal saline in DKA
Used when blood glucose falls below 250 mg/dL to prevent hypoglycemia.
Main risk of Dextrose in 5% normal saline
Fluid overload, especially in patients with cardiac or renal disease.
Indication for 3% Sodium Chloride solution
Severe dilutional hyponatremia or severe sodium depletion.
Key precaution for 3% Sodium Chloride administration
Administer cautiously and monitor closely to prevent pulmonary edema.
Skin turgor assessment location in older adults
Over the sternum or on the forehead.
Minimum hourly urine output rate in fluid volume deficit
At least 0.5 mL/kg/hr.
Frequency of assessing fluid overload patients for pulmonary edema
At least every 2 hours.
First priority assessment when muscle weakness is present
Check respiratory effectiveness.
Maximum recommended infusion rate for IV potassium
5 to 10 mEq/hour, never exceeding 20 mEq/hour.
Recommended dilution ratio for IV potassium administration
No greater than 1 mEq per 10 mL of solution.
Action if IV potassium infiltration is suspected
Stop infusion immediately, remove venous access, and notify the provider.
Why women have less total body water than men
Women have more body fat and less muscle mass.