Patho Ch 34: Chronic and Degenerative Neurological Disorders

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45 Terms

1
Neurons
Conduct electrical signals
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2
Glial cells
Phagocytose foreign matter and cellular debris
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3
Neuron has 4 major parts
Dendrites
•Cell body
•Axon
•Axon terminals
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4
how many axons does a neuron have
1
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5
what do axon terminals contain
neurotransmitters.
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6
Synapse
Space between neurons where neurotransmitters move
from one neuron to another.
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7
Types of neurotransmitters
Acetylcholine
• Norepinephrine
• Serotonin
• Dopamine
• Gamma amino butyric acid (GABA)
• Glutamate
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8
Dopamine
behavior, movement, memory; CNS
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9
Norepinephrine
Excitatory stress hormone
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10
Glutamate
Excitatory signal in CNS
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11
Myelin
Protective sheath around axon of some neurons; Acts like insulation around electrical wire.
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12
what is referred to as white matter
myelin
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13
Epilepsy
Chronic neurological disorder with recurrent
seizures ; disrupted channel activation leading to repetitive synchronous firing of neuronal action potentials
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14
Seizure
Sudden, abnormal, disorderly discharge of neurons
within the brain
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15
Generalized Seizures
Arises in one hemisphere and evolves
to involve both hemispheres
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16
Absence seizures
Client is unaware of seizure activity
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17
Focal
localized within 1 cerebral hemisphere. Stays in that
hemisphere.
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18
Clonic
Motor symptoms with sustained
rhythmical jerking
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19
Tonic
Muscles become tense or rigid.
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20
Atonic
Weak or limp muscles
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21
Myoclonus
Muscle twitching
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22
Epileptic spasms
Repeated flexion and extension of the
whole body.
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23
Non-motor symptom
Absence seizures” (staring spells with
no movement)
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24
Aura
Sensation before a seizure
• Could be described as a strange light,
unpleasant smell, confusing thoughts.
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25
Ictal period
Episode of the seizure;time
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26
Postictal
After seizure complete
• Person may be tired, confused,
nauseated, may have amnesia
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27
Primary headaches
Arise independent of any other medical illness or
traumatic cause
• Tension-type, migraine, and trigeminal autonomic
cephalgia
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28
Secondary headaches
Caused by another primary condition
• Head injury, vascular problems, medication side
effects, sinus disease, and tumors
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29
what is the most common primary headache
Tension Type Headache
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30
where are tension headaches position
Bilateral pain with mild to moderate pressure
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31
does tension headache worsen with activity
no
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32
Migraine Headache
Periodic, throbbing headaches
• Altered perceptions, nausea, and severe pain
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33
what makes migraines worse
movement
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34
Viral Meningitis
mumps, measles, herpes, West Nile virus.
• No vaccine
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35
S/S viral meningitis
Headache, nuchal rigidity, photophobia,
fever, chills, nausea/vomiting, altered level of consciousness,
hyperactive deep tendon reflexes, tachycardia, seizures, red
macular rash
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36
Bacterial Meningitis
otitis media, pneumonia, sinusitis
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37
Parkinson’s Disease
Progressive loss of dopamine-producing cells in the
basal ganglia
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38
what moderates movement such as posture, standing,
walking, writing.
Basal ganglia
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39
what stimulates muscle movement
Acetylcholine
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40
Dopamine depletion imbalance causes
unopposed acetylcholine (tremors, uncoordinated movements)
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41
Multiple Sclerosis (MS)
Chronic demyelinating disorder.
• Autoimmune inflammatory disorder: T cell-mediated
attack of myelin
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42
what does MS impact
Affects brain, spinal cord, and optic nerves
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43
what heals during remission of MS
Myelin damage
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44
MS characterized by
Characterized by remissions and exacerbations
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45
MS risks
Genetic predisposition, viral process, trauma, female, Northern
European descent, living in cooler climates
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