surface markers on T and B cells

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14 Terms

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CD2

It is involved in T cells activation

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CD3

Associated with T cell antigen receptor; role in TCR signal transduction

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CD4

Coreceptor for MHC-II

receptor for HIV

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CD5

Positive or negatice modulation of T and B receptor signaling

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CD8

Coreceptor for MHC class I

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CD10

Protease; marker for pre B CALLA

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CD16

Low affinity for Fc cell receptor, mediates phagocytosis and ADCC

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Cd19

Part of B cells Macrophages Coreceptor, signal transduction molecules that regulates B cell development and activation

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CD21

Receptor for complement component CD3

Part of B cell receptir and Cd19

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CD23

Regulation of igE synthesis; triggers release of IL1, Ik6, and GM-CSF from monocytes

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CD25

Receptor for Il2

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CD44

Adhesion molecule mediating homing to peripheral lymphoid organs

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CD45R

Essential in T and B cells Macrophages antigen- stimulated activation

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CD94

Subunit of NKG2- a complex involved in the inhibition of NK cell antibody