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What does the endocrine system consist of?
Glands which secrete hormones
What are hormones?
Small chemical molecules that are released into the blood stream
What do some tissues have for hormones?
Specific receptors
What does the pituitary gland do?
Tells the body what to do and tells the other glands to release their hormones
What does the thyroid gland release?
Thyroxine
What does thyroxine do?
Regulates metabolism, growth
What does the pituitary gland sometimes release to maintain levels within the body?
Thyroid stimulating hormoneT
What is the process of the pituitary gland releasing TSH known as?
Negative feedback
What do the adrenal glands release?
Adrenaline
What does the pancreas do?
Produces insulin, regulates blood glucose concentration
What do ovaries produce?
Oestrogen
What does the endocrine system rely on?
Hormones being transported by blood
When the hormones are released, do they act locally or generally and do they last long or short?
They act generally and last longer
What is menstruation?
The breakdown of the uterus lining
What does the uterus lining do in preparation for the egg?
Builds up
What is ovulation?
When the egg is released from the ovary
What does oestrogen do?
Stimulates the lining growth
What does progesterone do?
Maintains the uterus lining
Where is luteinising hormone (LH) produced?
Pituitary gland
What does LH do?
stimulates the release of the egg (ovulation)
Where is follicle stimulating hormone produced?
Pituitary gland
What does FSH do?
Stimulates the egg to mature in ovaries
What does homeostasis mean?
The regulation of conditions inside the body to maintain a stable internal environment, in response to both internal and external conditions
What do receptors do?
Detect a change
What do effectors do?
Carry out a response
What is blood-glucose concentration?
The amount of sugar in our bloodstream
What can a too high of glucose concentration cause?
damage to tissues
What are high glucose levels detected by?
The pancreas
What does insulin when released to tackle the high glucose concentrations?
Binds to certain receptors to absorb excess glucose
Where does insulin binding to glucose happen alot?
In the liver and muscles
What is glucagon?
A hormone that is released from the pancreas that increases blood glucose levels
What is glycogen?
A large molecule made up of glucose
What does glucagon bind to?
Liver cells in order to break down glycogen and release glucose into the blood
What is thermoregulation?
The control of internal body temperature
Where are the thermoregulatory receptors found?
In the skin and blood vessels
What happens when our body wants to warm up?
Blood vessels are constricted to conserve heat, contract muscles to make our hair stand on end, shivering
What happens when our body wants to cool down?
Blood vessels expand, hairs lie flat, sweat (causing the heat to evaporate off of our skin)
What is the function of the kidneys?
To filter the blood and remove waste that we do not want
What is deamination in terms of the kidneys?
The kidneys mainly remove urea which is made in the liver
What does the kidneys regulate?
Ions and water
What do kidneys have?
Nephrons and tubules which absorb small molecules (filtration)
What does the hypothalamus do?
Detects the concentration of water in the bloodstream
What does anti diuretic hormone (ADH) do?
Tells the kidneys to reabsorb more water
How is the kidneys process of filtration a negative feedback loop?
The body is constantly monitoring water levels and adjusting them to make them balance
What does blood constantly do through the kidneys?
Cycle through
How does blood travel into the kidneys?
Through the renal arteries
How does blood travel out of the kidneys?
Through the renal veins
What do the kidneys produce?
Urine
What does urine travel through?
The ureters into the bladder and released from the urethra
When filtering, what does everything pass through in the kidneys?
The glomerulus → bowman’s capsule → tubules
What are the consequences of kidney failure?
Waste substances build up in the body and the body is unable to regulate water and ion levels
What can mild kidney disease be treated with?
Medicines for life and kidney transplants
What is dialysis?
Artificial kidneys that filter patients blood
What are the problems with dialysis?
Time consuming, unpleasant, blood clots, infections, expensive
What are the benefits and risks of kidney transplants?
Cheaper, organ rejection
What does diabetes mean?
Patients cannot regulate blood glucose
What happens in type 1 diabetes?
The pancreas stops producing insulin
True or false, type 1 diabetes is lifelong.
True
What is the treatment for type 1 diabetes?
Injecting insulin into the abdomen or thigh
What happens in type 2 diabetes?
Cells become resistant to insulin meaning they wont take glucose from the bloodstream
What type of people is type 2 diabetes seen in?
Older people and those with an unhealthy diet
How can type 2 diabetes be prevented/helped?
Healthy diet and exercise