Cellular Adaptations, Damage & Necrosis

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This set of flashcards covers the key vocabulary related to cellular adaptations, damage, and necrosis as outlined in the lecture notes.

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33 Terms

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Atrophy

Decrease in the size of cells, tissues, or organs.

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Hyperplasia

Enlargement of an organ due to increased production rate of its cells.

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Hypertrophy

Enlargement of an organ due to an increase in the size of cells.

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Metaplasia

The change of a cell from one type to another type of cell.

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Dysplasia

Abnormal changes in the cell structure, indicating a precancerous condition.

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Neoplasia

New production of cells, often referring to tumors.

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Homeostasis

The stability and balancing of biological systems necessary for survival.

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Necrosis

Cell death caused by injury or ischemia, resulting in non-living tissue.

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Liquefactive Necrosis

The softening of necrotic tissue into a paste-like mush or watery debris.

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Coagulative Necrosis

Cell death typically caused by ischemia, characterized by tissue firmness.

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Caseous Necrosis

Tissue death with a cheese-like appearance, typically surrounded by inflammation.

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Gangrene

Tissue death caused by infection or lack of blood flow.

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Apoptosis

Normal programmed cell death that occurs as part of growth or development.

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Ischemia

A reduction in blood flow leading to low oxygen supply to tissues.

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Benign Prostatic Hyperplasia

An enlargement of the prostate gland due to hyperplasia.

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Left Ventricular Hypertrophy

Enlargement of the heart muscle due to increased workload.

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Chronic irritation

Prolonged exposure to harmful substances that may lead to metaplasia.

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Neoplasm

An abnormal mass of tissue that can be benign or malignant.

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Myocardial Infarction

Commonly known as a heart attack, caused by the interruption of blood supply.

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Tuberculosis

An infectious disease that can cause caseous necrosis in the lungs.

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Abscess

A localized collection of pus in tissues, resulting from infection.

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Fluid balance

The maintenance of the proper amount and composition of bodily fluids.

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Muscular atrophy

Loss of muscle mass due to underuse or immobility.

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Tissue death

The degeneration or necrosis of cells in an organ or tissue.

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Tumor

An abnormal growth of tissue that can present as neoplasia.

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Smokers' lung changes

Metaplastic changes in airway tissues due to chronic smoking.

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Granulomatous inflammation

An immune response characterized by the formation of granulomas.

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Programmed cell death

A controlled mechanism of cell death that occurs during normal development.

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Cellular stress

Physical or chemical stimuli that can lead to cellular adaptations or damage.

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Necrotic tissue

Tissue that has died due to injury or circulatory insufficiency.

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Hormonal stimulation

Signaling that can promote hypertrophy in certain tissues.

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Cellular dysfunction

Abnormal metabolic activities that can lead to dysplasia.

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Oxygen deprivation

A lack of oxygen supply, leading to necrosis or cellular injury.