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Peripheral nervous system (PNS)
Links CNS to body and to external environment
Sensory division
consists of sensory (afferent) neurons that detect and transmit sensory stimuli to CNS
Somatic sensory division
detects both internal and external stimuli
Visceral sensory division
relays internal information (like blood pressure) from organs of abdominopelvic and thoracic cavities
Motor division
consists of motor (efferent) neurons; carry out motor functions of nervous system
Somatic motor divison
responsible for voluntary motor functions; composed of lower motor neurons which directly trigger skeletalmuscle contractions
Visceral motor divison
responsible for maintaining many aspects of homeostasis by controlling involuntary motorfunctions in body
Sympathetic nervous system (fight or flight division)
involved in homeostasis activities surrounding physicalwork and visceral responses of emotions
Parasympathetic system (rest and digest division)
involved in digestion and maintaining body’s homeostasis at rest
Peripheral nerves
main organs of PNS; consist of axons of many neurons bound together by connective tissue
Mixed nerves
contain both sensory and motor neurons
Sensory nerves
contain only sensory neurons
motor nerves
contains mostly motor neurons
Spinal nerves
originate from spinal cord and innervate structures below head and neck
Anterior root
consists of motor neurons from anterior horn
Posterior root
consists of sensory neurons from posterior horn
Posterior root ganglion
Posterior root features a swollen area that houses cell bodies of sensory neurons
Epineurium
outermost layer of connective tissue that holds motor and sensory axons together
Fascicles
small groups of bundled axons surrounded by connective tissue called perineurium
endoneurium
Each individual axon within a fascicle is surrounded by its own connective tissue
Cranial nerves
attach to brain and mostly innervate structures in head and neck
Bell’s palsy
Common problem associated with facial nerve
Spinal nerve
short and divides into following 2 mixed nerves; both carry both somatic motor and sensory information
Posterior ramus
travels to posterior side of body
Anterior ramus
travels to anterior side of body and/or to an upper or lower limb
Nerve plexuses
Anterior rami of cervical, lumbar, and sacral spinal nerves each merge to form complicated networks of nerves
Hiccups
annoying spasms of diaphragm that cause a forcefulinhalation of air
Sciatic nerve
longest and largest nerve in body; contains axons from both anterior and posterior divisions of sacral plexus
Exteroceptors
usually close to body’s surface; detect stimuli originating from outside body
Interoceptors
usually found within body’s Interior ; detect stimuli originating from within body itself
Mechanoreceptors
depolarize in response to anything that mechanically deforms tissue where receptors are found
Thermoreceptors
exteroceptors, most of which are slowly adapting receptors
Chemoreceptors
can be either interoceptors or exteroceptors; depolarize in response to binding to specific chemical
Photoreceptors
special sensory exteroceptors found only in eye
Nociceptors
usually slowly adapting exteroceptors
Capsaicin
Hot peppers can make your mouth feel like it’s on fire; result of chemical in peppers
neuropathies
capsaicin may be applied as a topical cream to relieve pain of peripheral nerve disorders
Shingles
a viral infection caused by chickenpox virus, and other conditions
Types of thermoreceptors
usually small knobs at end of free nerve endings in skin
“Cold” receptors
respond to temperatures between
10 C and 40 C (50–104 F); in superficial dermis
“Hot” receptors
respond to temperatures between
32 C and 48 C (90–118 F); deep in dermis
Dermatomes
Skin can be divided into different segments
dermatome map
Dermatomes can be combined to assemble a
Referred pain
phenomenon whereby pain that originates in an organ is perceived as cutaneous pain
Upper motor neurons
neurons of primary motor cortex make decision to move and initiate that movement
Lower motor neurons
receive messages from upper motor neurons; in contact with skeletal muscle fibers
Reflexes
programmed, automatic responses to stimuli
Reflex arch
Occur in a three-step sequence of events; usually protective negative feedback loops
Monosynaptic reflexes (simple reflex)
involve only a single synapse within spinal cord between a sensory and motor neuron
Polysynaptic reflexes
involve multiple synapses
Patellar (knee-jerk) reflex and jaw-jerk reflex
are examples of simple stretch reflexes
Golgi tendon reflexes
polysynaptic reflexes; protect muscles and tendons from damaging forces
Flexion or withdrawal reflex
involves rapidly conducting nociceptive afferents and multiple synapses in spinal cord
Crossed -extension reflex
occurs simultaneously on opposite side of body for balance and postural support while other limb is withdrawn from a painful stimulus
Cranial nerve reflexes
polysynaptic reflex arcs that involve cranial nerves
Gag reflex
triggered when visceral sensory nerve endings of glossopharyngeal nerve in posteriorthroat are stimulated
Corneal blink reflex
triggered when a stimulus reaches somatic sensory receptors of trigeminal nerve in thin outer covering of eye (cornea)
Plantar reflex
Healthy adult will flex toes, a response known as
Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s disease
involves degeneration of cell bodies of motor neurons in anterior horn of spinal cord as well as upper motor neurons in cerebral cortex