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1
Ach is released by neuron
2
Ach crosses synaptic cleft and binds to Na+ channels on the sarcolemma
3
Na+ (sodium) channels open up voltage changes create action potential
4
Electric impulses (action potential) travels across membrane and down T-tubles into cell
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sarcoplasmic reticulum near T-tubles releases Ca2+
6
Calcium binds to protein troponin and changes shape to open binding site from myosin -trafomyosin get out!
7
Myosin cross bridges (beads) attach to action
8
Power stroke: myosin head pivot to pull actin using Atp and cause sarcomere to shorten
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Myosin contnues to pivot with addition and use of ATP
10
Signals end, calcium levels drop again because calcium is absorbed by sarcoplasmic reticulum
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Myosin releases actin and muscle relaxes