Lecture 3 - Brain cell communication & measurement techniques

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12 Terms

1

What is the resting membrane potential of a neuron?

The resting membrane potential is approximately -70 mV, maintained by diffusion, electrostatic pressure, and the sodium-potassium pump.

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2

How does the sodium-potassium pump maintain resting potential?

It pumps 3 Na+ ions out of the cell and 2 K+ ions into the cell against their concentration gradients, requiring ATP.

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3

What triggers the opening of voltage-gated Na+ channels during an action potential?

The membrane potential reaching a threshold of -55 mV.

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4

Define the "all-or-none law" of action potentials.

The strength of the action potential is independent of the stimulus intensity, and the action potential is always the same size.

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5

What is saltatory conduction?

The jumping of action potentials from one node of Ranvier to the next in myelinated axons, which speeds up signal transmission.

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6

Name three methods of terminating neurotransmitter action.

Diffusion, enzymatic degradation, and reuptake.

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7

What is the main difference between ionotropic and metabotropic receptors?

Ionotropic receptors act faster and are involved in signaling, whereas metabotropic receptors act slower and are involved in modulation.

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8

What are EEG and ERPs used for?

EEG measures electrical brain activity with high temporal resolution. ERPs detect brief changes in EEG signals in response to stimuli.

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9

How does functional MRI (fMRI) measure brain activity?

It detects changes in blood oxygenation levels (BOLD signal) to infer neural activity.

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10

What is a key advantage of MRI over CT scans?

It provides better resolution and structural details without using ionizing radiation.

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11

What is transcranial magnetic stimulation (TMS) used for?

It non-invasively stimulates or inhibits brain regions and is used for research and treatment of conditions like depression.

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12

Describe the relationship between neurotransmitter reuptake inhibitors and their effects.

Reuptake inhibitors, like SSRIs, block the reuptake of neurotransmitters, increasing their availability in the synapse.

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