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The Cell Cycle
The repeated sequence of growth and division in eukaryotic cells.
Interphase
The longest stage of the cell cycle; includes G1, S, and G2 phases.
G1 Phase
Cell grows and carries out normal functions, preparing for DNA replication.
S Phase
DNA is replicated, creating two identical copies.
G2 Phase
Prepares for mitosis by producing proteins and microtubules.
Mitosis
The division of the nucleus into two identical nuclei.
Cytokinesis
The division of the cytoplasm, resulting in two identical daughter cells.
Chromatin
Loose, readable DNA present during interphase.
Chromosome
Supercoiled DNA present during mitosis.
Sister Chromatids
Identical copies of DNA connected by a centromere.
Centromere
The region where sister chromatids are connected.
Prophase
Chromosomes condense, the nuclear envelope breaks down, and spindle fibers form.
Metaphase
Chromosomes align at the cell's equator (metaphase plate).
Anaphase
Sister chromatids are pulled apart to opposite poles by spindle fibers.
Telophase
Chromosomes decondense, nuclear envelopes reform, and two nuclei form.
Cleavage Furrow
The structure in animal cells where the cell membrane pinches to divide.
Cell Plate
The structure in plant cells where a new cell wall forms during cytokinesis.
Cyclins
Proteins that regulate the progression of the cell cycle.
Cyclin-Dependent Kinases (CDKs)
Enzymes that bind to cyclins to control cell cycle checkpoints.
Cancer
Uncontrolled cell division due to malfunctioning cell cycle regulation.
Benign Tumor
A tumor that is encapsulated and does not spread.
Malignant Tumor
A dangerous tumor that spreads through the body (metastasis).
Apoptosis
Programmed cell death to remove damaged or unnecessary cells.
Stem Cells
Unspecialized cells that can differentiate into specialized cell types.
Pluripotent Stem Cells
Stem cells that can differentiate into most cell types.
Multipotent Stem Cells
Stem cells that can differentiate into a limited range of cell types.
Induced Pluripotent Stem Cells (iPSCs)
Reprogrammed adult cells that act like embryonic stem cells, Skin cells can be reprogrammed into embryonic stem cells; Pluripotent
Carcinogen
A substance that can cause cancer by damaging DNA.
Metastasis
The spread of cancer cells to other parts of the body.
G0 Phase
A resting phase in the cell cycle where cells do not divide (e.g., nerve cells).
Mitosis Checkpoint
Ensures sister chromatids separate correctly during mitosis.
DNA Synthesis Checkpoint
Ensures DNA replication is error-free during S and G2 phases.
Cell Growth Checkpoint
Ensures the cell is large enough to divide after G1.
Embryonic Stem Cells
Pluripotent; Blastocyst
Adult Stem Cells
These are found in mature body tissues (like bone marrow and fat cells), They are used to maintain and repair the same kind of tissue in which they are found; Multipotent
Perinatal Stem Cells
Stem cells found in the umbilical cord or amniotic fluid, Doctors can preserve these after birth to be used later in life by child!; Pluripotent