Test 1 MCQs Diagram | Quizlet
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29 Terms
Which type of analysis would identify changes to the chromosomal sequences of DNA in the nucleus of a cell?
Genomics
3 multiple choice options
The mRNA transcribed from a gene will be complementary and anti-parallel to which strand?
The Non-coding strand of the DNA
3 multiple choice options
TAF is a part of which of the following?
TFIID
3 multiple choice options
Which of the following is considered part of the 3' UTR?
Terminator region
3 multiple choice options
Which of the following is NOT required for proper splicing of introns in most mRNA molecules?
GT dinucleotide at 5' end of preceding exon
3 multiple choice options
Imagine you were doing a PCR reaction and you messed up while programming the machine and the PCR program looked like the one shown below:
95* - 1 min
72* - 1 min
-- Repeat 35 times
Which of the following would explain why your PCR failed?
Your program never allowed primers to bind
3 multiple choice options
Which enzymatic function of DNA Polymerase I removes RNA primers?
5'→3' exonuclease
3 multiple choice options
Polyadenylation begins with binding of ______ near a six-nucleotide mRNA sequence, AAUAAA, downstream of the stop codon.
the cleavage and polyadenylation specificity factor (CPSF)
3 multiple choice options
Which of the following uses transcription factors that bind to ICRs within the transcribed region of the gene?
RNA Pol III
3 multiple choice options
The sequence 5' - UCGCCCG- 3' is part of the stem in a stem-loop structure. What is the sequence that would base pair, forming the other complementary side of this "stem"?
3'-AGCGGGC-5'
3 multiple choice options
Which is NOT a step in bacterial tRNA processing?
Adding bases to 3'
3 multiple choice options
Which enzyme transcribes most snRNA genes?
RNA Polymerase III
3 multiple choice options
What would most likely occur if a DNA mutation completely changed an enhancer sequence into a silencer?
Transcriptional rate would decrease
3 multiple choice options
What bond is formed by Guanylyl Transferase?
5'-5' bond
3 multiple choice options
Determine the -35 consensus sequence for the following sequences (just the individual -35 consensus sequences are shown):
Gene 1 TTGACT
Gene 2 TTGCTT
Gene 3 GCGCTA
Gene 4 TTGATA
Gene 5 TTTACA
TTGATA
3 multiple choice options
What happens if the 9-mer sequences of OriC are deleted?
DnaA cannot bind → initiation fails
3 multiple choice options
Which sigma factor recognizes housekeeping promoters?
σ70
3 multiple choice options
Which is the largest?
Replisome
3 multiple choice options
Sickle cell disease (SCD) is found in populations whose ancestral homes are in the malaria belt of Africa and Asia. SCD is an autosomal recessive disorder that presents in individuals homozygous recessive for a mutant beta-globin gene allele. Data on one affected population indicates that approximately 21 in 1000 newborn infants have SCD. In this population, what is the expected frequency of the dominant allele in this population?
0.855
3 multiple choice options
Which statement is TRUE of type I introns?
Require snRNPs; excised as lariat
3 multiple choice options
Which step happens first in transcription initiation?
TFIID binds to the TATA box
3 multiple choice options
Which of the following BEST describes the enzymatic activity of Torpedo in transcription termination?
5'→3' exonuclease
3 multiple choice options
Which DNA form has a left-handed twist?
Z-form
3 multiple choice options
What is the name of the endonuclease used in DNA footprinting?
DNase I
3 multiple choice options
Why does a full-length eukaryotic gene fail in bacteria? (select all)
Promoter not recognized; Introns not removed; Sequences for efficient translation initiation are not present.
2 multiple choice options
TERM
In the image below, three mRNA transcripts are shown on the left. Which of the possible outcomes on the right is an example of Intergenic Transplicing?
DEFINITION
Bottom
3 multiple choice options
TERM
Click the middle circle; I can't get rid of this one
DEFINITION
Middle (Click on that circle; I cant get rid of this)
TERM
Click the Top Circle; I can't get rid of this one
DEFINITION
Top (Click on that circle; I cant get rid of this)
TERM
Click the Rectangle; I can't get rid of this one
DEFINITION
All Three (Click the Rectangle; I cant get rid of this)