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Which best defines nociception
Neural encoding and processing of noxious stimuli
What best describes nociceptors
Free nerve endings found in skin muscle joints bone and viscera
Which fiber type mediates first fast sharp pain
A delta fibers
Which does NOT directly activate TRPV1 channels
Prostaglandins
Which axon type has the slowest conduction velocity
C fibers
Which mechanoreceptor is rapidly adapting and detects vibration
Pacinian corpuscle
How is the dorsal root ganglion neuron classified
Pseudounipolar
Which receptor primarily signals muscle tension
Golgi tendon organ
Which pathway carries discriminative touch
Dorsal column medial lemniscal system
The VPM nucleus of the thalamus relays sensory input from where
Face
Type II A delta nociceptors respond best to what
Thermal heat stimulation
Which Rexed laminae receive primary nociceptive input
Laminae I II and V
Where do second order neurons cross in the anterolateral system
Level of the spinal cord
What is hyperalgesia
Increased sensitivity to painful stimuli
What is wind up
Increased excitability of dorsal horn neurons
Which tract contributes to affective motivational aspects of pain
Spinoreticular tract
What causes allodynia
Central sensitization allowing innocuous stimuli to activate pain pathways
Which photoreceptor mediates scotopic vision
Rods
What mediates the dark current in photoreceptors
cGMP gated sodium calcium channels
What effect does light have on photoreceptors
Hyperpolarization
Which fibers travel in Lissauer tract
Pain and temperature afferents
A unilateral spinal cord lesion causes what pattern
Contralateral pain loss ipsilateral touch loss
What does the fasciculus gracilis carry sensory information from
Lower body
How are Group Ia afferents best described
Rapidly adapting large myelinated fibers
Which receptor is slowly adapting and encodes sustained pressure
Ruffini ending
The medial lemniscus forms after synapse in which structure
Medulla
Which structure lacks photoreceptors and creates the blind spot
Optic disc
What is the fovea specialized for
High visual acuity
Which retinal cells provide lateral inhibition
Horizontal cells
ON center ganglion cells increase firing when what occurs
Light increases in the center
Which cone type is absent from the foveola
S cones
What causes deuteranopia
Loss of medium wavelength cones
Which retinal cells fire action potentials
Ganglion cells
Myopia occurs when the focal point falls where
In front of the retina
Accommodation for near vision requires the lens to do what
Become more curved
Capsaicin produces analgesia through what mechanism
TRPV1 desensitization
Which pathway orients the eyes and head toward painful stimuli
Spinotectal tract
Rapidly adapting mechanoreceptors primarily encode what
Changes in stimulation
Which neurons control intrafusal muscle fiber tension
Gamma motor neurons
What is unique about visceral nociceptors
They include silent nociceptors
Paleospinothalamic pathways are associated with what type of pain
Dull burning pain
Which thalamic nucleus relays body touch information
VPL
How is the visual image formed on the retina
Inverted and curved
Cataracts impair vision by affecting which structure
Lens
How do rods differ from cones
Rods are extremely light sensitive
Central sensitization allows what phenomenon
Innocuous stimuli to produce pain
Which structure contains sensory neuron cell bodies
Dorsal root ganglion
What type of potential is characteristic of sensory receptors
Graded
What does plasticity in primary somatosensory cortex refer to
Functional expansion after repeated stimulation
How is the primary somatosensory cortex organized
Columns as functional module