BIO 211 final
fertilized egg
zygote
when a zygote divides and forms a ball of cells, it is called an
embryo
cells acquire specialized properties during
differentatiation
why do different cell types have different structures and functions?
they contain different molecules
all cells are genetically
genetically equivalent (they contain the same genes)
which of the following is true of the cloning experiment that resulted in Dolly the sheep?
A) Dolly was genetically identical to the egg-cell donor. \n B) Dolly was cloned by fusing an egg with an embryonic stem cell. \n C) Dolly was infertile, which indicated incomplete nuclear reprogramming. \n D) Dolly was cloned by using a differentiated cell fused to an egg from another individual. \n E) Dolly was cloned by fusing the nuclei from two separate eggs harvested from the same individual.
D
changes in the parents genes (long term smokers, older parents, etc) not caused solely by genes
epigenetic inheritance
what is the most important thing in epigenetic inheritance
chromatin condensation patterns
when an embryonic animal cell becomes dedicated to a cell specalization path (when it goes from a stem cell to a bone, liver, heart, brain cell)
commitment
what are the steps from embryonic animal cell to specalization
cell → committed → determined → differentiated
cells are moved in the embryo once they are
determined
what causes cells to differentiate?
master regulator is a gene product that determines what they become
what type of cells stay undifferentiated
stem cells
what do stem cells do
may replace skin, blood, and gut cells that die
repair wounds
create a supply of disease fighting cells
pluripotent embryonic stem cells can develop into _____ cell types
all
Pluripotent means
embryos are destroyed in order to obtain them
multipoint means that cells can develop into ____ cell types
few
where are multipotent cells located
bone marrow and intestines
what are stem cells in plants called?
meristems
name the 5 essential cellular processes that lead to organism development
cells divide (like as an embryo)
signal to one another what they are (like hair, eyes, bone, arm, leg)
begin to express certain genes than other (hair color, gender)
move, expand, contract in different directions (to go from circle to baby shaped)
some cells die
cells respond to signals from _______ cells to control cell division
other
cells interact ______ during development through. _________ molecules
constantly
signaling
name the 2 mechanisms for determining cell fate
cytoplasmic determinants (regulatory molecules that are unequally distrubted to the cells produced from cell division)
induction (one daughter cell receives it, other one doesn’t)
during gastrulation, cells rearrange into _____ layers
three
what controls cell shape and location in plant cells?
cel wallswh
what are the three layers that form at gastrulation
ectoderm
mesoderm
endoderm
what is formed from the ectoderm
ecto means outside so think skin, teeth, nails
what forms from the mesoderm
mess means middle so think blood, bones, facial muscles,
what does from the endoderm
endo means inside so think stomach, lungs
what type of cells are killed during development (apoptosis)
webs between does
framework for central nervous system
secreted molecule that induces cell fate decisions in recipient cells in a concentration dependent manner
signaling molecule that acts directly on cells to produce specific cellular responses depending on its local concentration.
morphogens
what do segmentation genes do
divide the embryo into segments (like a worm)
determine the number and size of each segment
3 types of segmentation genes
gap genes
pair rule genes
segment polarity
selector genes are also called
hox genes
hox genes determine
the segmentation (think thigh, calf, ankle, foot, toes) of each appendage
as you go up evolution from worm to mouse to monkey to human, the number of hox clusters
increases
mutations in the hox genes result in the ________ of one body segment into another
change
who was dolly
sheep that was clone
what happens if the bicoid protein is missing?
genes fuck up and fruit flies can be born without head or neck