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spontaneous ventilation
Breaths that are initiated by the patient (i.e. patient cycled), and volume delivery is determined by the patient (patient cycled). Volume, flow, pressure delivery is based on patient demand/lung characteristics rather than on a value set by the ventilator operator
-The patient controls the timing and the Vt.
**is the body’s mechanism for conducting air in and out of the lungs
What happens to intrapleural pressure during spontaneous ventilation?
decreases from -5cm H20 at end expiration to -10cmH20 at end inspiration
Normal: -5 to -10cmH20
Equation of motion describes relationships between what
describes the relationships between pressure, volume, and flow during a spontaneous or mechanical breath
elastance
the tendency of a structure to return to its original form after being stretched or acted on by an outside force
compliance
the relative ease with which the structure distends
resistance
measurement of the frictional forces that must be overcome during breathing
disease that causes an increase in compliance
emphysema
static compliance formula
Cstat=Vt/(Pplat-PEEP)
airway resistance formula
Raw=PIP-Pplat/flow
*flow needs to be L/sec
Values for compliance
Normal: 50-170mL/cm H20 (0.05-0.17L/cm H20) (spontaneously Breathing)
Intubated:
Men: 40-50mL/cm H20
Women: 35-45mL/cmH20
Values for airway resistance
Normal Value: 0.6-2.4cmH20/L/sec
Intubated: approx. 6 cmH20/L/sec or higher
Ideal Body Weight
Men quick way: 50+2(every inch over 5ft)
Men: 106+6(H in inches-60)/2.2 for kg
Women easy way: 45+2(every inch over 5ft)
Women: 105+5(H in inches-60)/2.2 for kg
How do PIP and Pplat change with changes in compliance?
As PIP and Pplat increase, compliance decreases
How do PIP and Pplat change with airway resistance?
As PIP increases and Pplat stays the same(constant), airway resistance increases
What is occurring when there is an increase in PIP but not an increase in Pplat or there’s an increase in both?
-Increase in PIP, but no increase un Pplat= increase in airway resistance
-Increase in both PIP/Pplat=decreased compliance
What happens to Pplat in ARDS patients?
Pplat will increase because compliance is decreasing causing stiff and hard lungs to inflate
what phase is Pplat measured?
Inspiratory pause (at end inspiration before exhale)
-Measured after a breath has been delivered to the patient and before exhalation begins
What conditions are associated with an increase airway resistance?
asthma, chronic bronchitis, emphysema, COPD, tumors, thick secretions
Time constants
1 time constant equals the amount of time it takes for 63% of the volume to be inhaled or exhaled
2 time constants represent that amount of time for about 86% of the volume to be inhaled or exhaled
3 time constants equal the time for about 95% to be inhaled or exhaled
4 time constants is the time required for 98% of the volume to be inhaled or exhaled
5 time constants=100%
definition of time constant
length of time lung units require to fill and empty
Intrinsic PEEP
Auto-PEEP
side effect of positive pressure ventilation, which leads to air trapping in the lungs
-Patient does not have enough time to exhale completely before the ventilator delivers another breath
Extrinsic PEEP
PEEP applied by the operator on the ventilator
Total PEEP
Intrinsic PEEP + Extrinsic PEEP
Expiratory Pause
pause at end of exhale before next breath given to measure auto-PEEP
Inspiratory Pause
Measures plateau pressure or Pplat
Measured after a breath has been delivered to the patient and before exhalation begins
Pplat also known as inflation hold or inspiratory pause
User interface
Control panel on vent
-Located on the surface of the vent and is monitored and set by the vent operator
-Has various knobs or touch pads for setting components, such as tidal volume, rate, inspiratory time, alarms, and FiO2
-The controls regulate 4 ventilatory variables: flow, volume, pressure, and time
How many variables can a vent control at one time?
1 (pressure, volume, flow, or time)
An increase in airway resistance during volume-controlled ventilation will cause what
a large increase in PIP due because more pressure is needed to deliver the set Vt
Raw ↑ → PIP ↑, VT same
An increase in airway resistance during pressure-controlled ventilation will cause what
lower Vt because there will not be enough pressure to overcome the resistance and inflate lungs fully
Raw ↑ → VT ↓, PIP same (because pressure is fixed)
trigger
variable beginning inspiration
limit
maximum value that a variable (pressure, volume, flow or time) can attain
cycle
variable ending inspiration
What Pt trigger requires the least amount of WOB for patient?
flow triggering
What are the two most used patient-trigger variables?
Flow and pressure
What happens when we increase the peak flow (Vmax)?
Decreased I time, increased E time
What happens when we decrease peak flow (Vmax)?
Increase I time, decrease E time
Variable that controls exhalation
baseline variable
How are Homecare Vents powered/classified?
electrically/battery powered
Negative pressure ventilation risks/supplemental O2 problems
blood pooling and reduced venous return
cannot easily access pt to bathe/turn
-will not help severe shunting
-oxygen toxicity leading to atelectasis
IMV Mode (SIMV mode)
-time or patient triggered
-some full mechanical breaths, some spontaneous
-will not give full support to spontaneous breaths
-used to wean
allows the patient to spontaneously breathe between mandatory, machine, breaths at any desired baseline pressure without receiving mandatory breaths
AC mode
-time or patient triggered
-set frequency of mechanical breaths but pt can trigger their own
-if pt triggers, vent will give full set Vt, FiO2, PEEP
caution for hyperventilation
CMV mode
-time triggered and cycled
-vent does ALL of the work-locks pt out
-only used if the patient makes no effort at all
what is the use of an HME?
-artificial nose to provide humidity for mechanical ventilation
-can accumulate secretions/moisture
-increasing Raw
-can cause auto-PEEP and increase WOB
Volume control mode
will deliver a set Vt and flow but pressure will vary
Pressure control mode
will maintain a certain pressure but volume and flow will vary
Transairway pressure
Formula: PTA=Paw−Palv
(Pta) =PIP-Pplat ***
Def: Pressure difference between the airway opening and the alveolus
-the pressure difference between the mouth and the alveoli
-pressure needed to get air into the airways
-Pressure needed to overcome airway resistance.
Transpulmonary pressure
Transalveolar
Def: is the pressure difference between the alveolar space and the pleural space
-pressure required to maintain alveolar distention
Transrespiratory pressure
Def: is the pressure difference between the airway opening and the body surface
-Pressure required to inflate the lungs during positive pressure ventilation
Normal cuff pressures
20-25mmHg
27-34cmH20
Causes of low-pressure alarm
-leak in circuit
-patient disconnect
Fix it: reconnect circuit, seal leaks, check cuff, confirm tube placement.
causes of high pressure alarm
-coughing/bronchospasm
-increased airway resistance
-decreased compliance
-pt biting tube
Fix it: suction, unkink tubing, drain water, replace HME, treat bronchospasm, manage compliance issues, use bite block.
Minute ventilation formula
Ve=Vt*f
ARDS is a pathological condition that is associated with a reduction in lung compliance. The formula for static compliance (CS) utilizes the measured plateau pressure (Pplateau) in its denominator (CS = VT /(Pplateau - EEP). Therefore, with a consistent exhaled tidal volume (VT) ,an elevated Pplateau will decrease CS.
Alveolar pressure during spontaneous inspiration?
About −1 cmH₂O.
causes of increased airway resistance
Secretions, bronchospasm, mucosal edema, mucosal inflammation.
Fix it: Tracheobronchial suctioning will remove any secretion buildup and a beta-adrenergic bronchodilator will reverse
bronchospasm.
Does increasing PEEP fix airway resistance problems?
No — compliance is normal; Raw is the issue.
Rising plateau pressure indicates what?
decreased lung compliance
ARDS affects compliance how?
ARDS decreases lung compliance.
dynamic compliance
pulmonary compliance during gas flow,
formula-Vt/(PIP-PEEP)
sensitivity
Setting that controls how easy/hard it is to trigger breath
time
Trigger variable in a controlled mode is
Time is the ventilator trigger variable.
Pulmicort dosage
0.5mg or 0.25mg
Xopenex dosage
0.31mg, 0.63mg, 1.25mg