Inhalation Anesthetics

Effects and Adverse Effects of Halogenated Inhalation Anesthetics

Dose related CNS depression, Hypothermia, Paddling, excitement, and muscle fasciculations during recovery

The tendency of an inhalation anesthetic to vaporize to its gaseous state

Vapor Pressure

High vapor pressure is a _______ agent

Volatile

low vapor pressure is a _______ agent

non volatile

Low blood-gas partition coefficient

Faster induction and recovery

High blood-gas partition coefficient

slower induction and recovery

Used to determine the average setting on the vaporizer that will produce surgical anesthesia

Minimum Alveolar Concentration (MAC)

isoflurane mac

1.30% to 1.63%

isoflurance color

purple

sevoflurane mac

2.34% to 2.58%

sevoflurane color

yellow

desflurane mac

7.2% and 9.8%

desflurane color

blue

least commonly used because it is expensive and is it very pungent - irritating to the lungs

desflurane

can cause hyperventilation, hypertension, arrhythmia and lowers seizure threshold

doxapram

Reflex closure of the glottis in response to contact with an object or substance

Laryngospasm

Laryngospasm

May lead to cyanosis or hypoxemia