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a specialized area of biology that deals with living things ordinarily too small to be seen without magnification
Microbiology
Microorganisms include: (8)
Bacteria, Archaea, Protozoa, Fungi, Helminths, Algae, Viruses, Prions
Why are microbes very easy AND very difficult to study? (5)
Reproduce rapidly, can be grown quickly in large populations in the lab, cannot be seen directly, analyzed through indirect means, viewed through microscopes
Eukaryotes
“true nucleus” (and organelles)
Bacteria
single-celled, no true nucleus
Archaea
single-celled, no true nucleus, distinct from bacteria
Prokaryotes
bacteria and archaea, “pre-nucleus”
Akaryotes
“no nucleus” (alternate term for prokaryotes)
Microbes are _____
(ubiquitous) everywhere
Microbes are _____ (size)
small size but large in number
____ are the most abundant cellular organisms in the ocean
Bacteria
_____ are the most abundant inhabitants of the ocean
Viruses
Bacteria and fungi live together with plants and help ________
in obtaining nutrients and water
______ is when humans manipulate microorganisms to make products in an industrial setting.
Biotechnology
Examples of biotechnology are:
Genetic Engineering, Recombinant DNA Technology, and Bioremediation
Genetic Engineering is when _____
manipulates the genes to create new products and genetically modified organisms (GMOs)
Recombinant DNA Technology is when ______
Transfer genetic material from one organism to another and deliberately alter DNA
Bioremediation is when ______
Uses microbes already present or introduced intentionally to restore stability or clean up toxic pollutants
True or False: The vast majority of microorganisms that associate with humans are harmless or beneficial
True
What are microbes that cause disease
Pathogens
Over _____ microbes cause disease
2,000
True or False: Infectious diseases are common causes of death worldwide
True
When did the Genetic Identification of the Human Microbiome start
2010 and Beyond
Produced by the Human Microbe Project and set the stage for new knowledge of our microbial guests and their role in our overall health and disease
Genetic Identification of the Human Microbiome
What are monomers
subunits of macromolecules
What are polymers
chains of various lengths of monomers
Macromolecules are what size, and how many main types are there
Very large; 4 main types
What are the 4 main types of macromolecules
Carbohydrates, Lipids, Proteins, and Nucleic Acids
Carbohydrates end with the suffix ___
-ose
Examples of carbohydrates
Glucose, fructose, lactose, and sucrose
____ Contribute to structural support and protection; serve as nutrient and energy storage
Polysaccharides (complex carbohydrate)
__ is the cell wall of plants and many algae
Cellulose
__ is an important component of culture media
Agar
__ is the cell wall found in fungi
Chitin
__ is the component of bacterial cell wall
Peptidoglycan
__ is the component of gram-negative cell wall
Lipopolysaccharide
__ is the protective outer layer; role in the attachment of cells to other cells or surfaces
Glycocalyx
Triglycerides are a __
important storage lipid
__ is composed of a single molecule of glycerol bound to the three fatty acids
Triglycerides (lipid)
Fatty acids can be _ or _
saturated or unsaturated
Triglycerides are stored in long-term concentrated form as ___ or ___
droplets or globules
True or False: Triglycerides yield twice as much energy per gram as other storage molecules (carbohydrates)
True
hydrophilic means __
“water-loving” head
Hydrophobic means ___
“water-fearing” tail
When exposed to an aqueous solution, membrane lipid’s ____
Charged heads are attached to the water, Non-polar tails are repelled from the water, and naturally assume a single or double layer (bilayer)
What are complex ringed compounds found in cell membranes and as animal hormones
Steroids
What reinforces the cell membrane in cells that lack a cell wall
Cholesterol
What are found in the cell wall of bacteria that cause tuberculosis and leprosy, contributing to their disease-causes potential
Waxes
Predominant organic molecule in cells
Proteins
How many different amino acids are proteins composed of
20
A molecule composed of short chains of amino acids
Peptide
Usually has more than 20 amino acids and is often a smaller subunit of a protein
Polypeptide
True or False: The structure of a protein determines its function
True
Type, Number, and order of amino acids in the chain
Primary Structure
What protein structure arises when various functional groups (R groups) interact by forming hydrogen bonds
Secondary Structure
Two types of protein secondary structure
Alpha Helix and Beta Pleated Sheet
What protein structure is created by additional bonds between functional groups
Tertiary Structure
What protein structure is when more than one polypeptide forms a large, multiunit protein
Quaternary Structure
Each protein develops a unique shape, and its surface displays a distinct pattern of ___ and ___ on the surface
pockets | bulges
Proteins can only interact with molecules that fit its particular _____, like a lock and key
surface features
Catalysts for all chemical reactions in cells
Enzymes
Glycoproteins with specific regions of attachment for bacteria, viruses, and other microorganisms
Antibodies
The functional three-dimensional form of a protein
Native State
Disruption of the native slate of a protein
Denatured
Denaturing agents include ___, ____, ____, and _______.
heat, acid, alcohol, some disinfectants
Contains a special genetic program with detailed and specific instructions for each organism’s heredity
DNA
“helper” molecules responsible for carrying out DNA’s instructions
RNA
What is the gentic material for most viruses
RNA
Formed by two long nucleotide strands linked by hydrogen bonds between nitrogen bases
Nucleic Acids
Adenine always pairs with _____
Thymine
Guanine always pairs with
Cytosine
Made up of 3 parts: Adenine, Ribose, 3 high-energy phosphate molecules
Adenine Triphosphate
Give off energy when the bond is broken between the second and third phosphate
Adenosine Triphosphate
In Adenosine Triphosphate, energy is ____ and ___ for chemical reaction
released and stored
The science of classifying living things
Taxonomy
The process of discovering and recording the traits of organisms so that they may be recognized or named and then classified
Identification
The assignment of scientific names to the various taxonomic categories and to individual organisms.
Nomenclature
The orderly arrangement of organisms into a hierarchy
Classification
Scientific name is a combination of the ___ and ___ names.
Genus and species
Scientific names are _____ when they are written in print and _____ when they are written by hand.
Italicized | underlined
When the name is abbreviated, the ____ name is abbreviated to the first initial followed by a period and the full _____ name is written
genus | species
Order of the classifcations
Domain-Kingdom-Phylum-Class-Order-Family-Genus-Species
How Organisms (Bacteria) are different from Eukaryotes
The way their DNA is packaged: lack of nucleus and histones
The makeup of their cell wall: peptidoglycan and other unique chemicals
Their internal structures: lack of membrane-bound organelles
All Bacteria cells contain
Cytoplasmic membrane, cytoplasm, ribosomes, cytoskeleton, one (or a few) chromosomes
Most bacteria contain
Cell wall, A surface coating called a glycocalyx
Bacteria can:
Be independent unicellular organisms
Some act as a group in colonies or biofilms
Some communicate through nanotubes
Bacteria have an average size of _____
1 µm (micron)
Cell is spherical or ball shaped, can be perfect sphere, oval, bean-shaped or even pointed
Coccus
A cell that is cylindrical is termed a rod, depending on the species, they can be blocky, spindle-shaped, round-ended, long and threadlike (filamentous), or even club shaped or drumstick-shaped
Bacillus
When a rod is short and plump, it is called a _____
coccobacillus
Singly occurring rods that are gently curved
Vibrio
A bacterium having a slightly curved or spiral-shaped body, a rigid helix, twisted twice or more along its axis (like a corkscrew)
Spirillum
Another spiral cell, a more flexible form that resembles a spring
Spirochete