Mechanism of HCl Formation

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4 Terms

1
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  • Parietal cells pump H+ (from carbonic acid breakdown) into

  • the stomach lumen via H+/K+ ATPase (proton pumps)

2
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HCO3− is exported back to blood via Cl− and HCO3− antiporter

Resulting increase of HCO3− in blood leaving stomach is referred to as alkaline tide

3
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Cl− is pumped out to lumen to

join with H+, forming HCl

4
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when Parietal cells pump H+ into stomach lumen

H+ is pumped into stomach lumen, HCO3− is exported back to blood via Cl− and HCO3− antiporter