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Insulin
Decreases blood glucose by increasing glucose uptake in the muscle; increasing glucose uptake in the adipose tissue; increasing glycogenesis in the liver; increasing lipogenesis in the adipose tissue.
Alcohol in red wine
Will likely undergo glycolysis.
Type 1 diabetic liver metabolism
Resembles that of someone who is fasting.
Beta-oxidation of long-chain fatty acids
8 acetyl CoA are produced from a 16-carbon fatty acid; The process generates reducing equivalents; The process requires NAD+ and FAD.
Fatty acids synthesis
Can be synthesized from C-skeletons derived from amino acids; Acetyl CoA; Glucose.
Failure of liver
Leads to high blood ammonia.
Gluconeogenesis
Requires energy.
Glycolysis
A molecule of glucose is converted to 2 molecules of pyruvate.
Overexpression of UCP1
Will increase energy expenditure.
Glycogenesis
Is stimulated by insulin.
Nutrient breakdown in the mouth
Carbohydrates start their chemical breakdown.
Primary function of the epiglottis
To block the larynx and protect airways during swallowing.
Functions of the stomach
It churns, mixes, and grinds food to produce chyme; It secretes hydrochloric acid, which aids digestion and absorption; It releases chyme in small portions through the pyloric sphincter to the small intestine; It secretes protease (enzymes that breakdown proteins).
Functions of muscles in the digestive system
Segmentation; Sphincter contractions; Peristalsis.
Most digestion and absorption
Occurs in the small intestine.
Glucose uptake by enterocytes
Occurs through active transport, while fructose is taken up through facilitated transport.
Goblet cells
Secrete mucus.
Water-soluble nutrients absorption
After absorption, they are released into the blood, delivered to the liver through the portal vein.
Coordination of digestive system functions
Is managed by the nervous and hormonal systems.
Pancreatic amylase
Breaks down starch.
Isomaltase
Breaks down dextrins.
Lipase
Breaks down triglyceride (triacylglycerol).
Pepsin
Breaks down protein.
Satiation
The biological sensation that prompts stopping eating during a meal.
Nutrient class with largest energy difference
Lipids have the largest difference between gross and metabolizable energy.
Satiety hormone from adipose tissue
Leptin.
Component of energy expenditure
The thermic effect of food is modulated by macronutrient composition.
Orlistat mechanism of action
It decreases the difference between digestible energy and metabolizable energy of food consumed.
Tom's BMI
Is 36.
Tom's estimated energy requirement
For very active 29-year-old male is closest to 4880 kcal/day.
Incorrect statement about BMI & Diabetes Risk
The prevalence of diabetes is much higher in women than in men of normal weight (based on BMI).
EER equations
Show age-related decline in energy needs is more pronounced in men than women.
Most accurate method to assess caloric needs
Of a bedridden patient is indirect calorimetry.
Conditionally essential amino acids
Cysteine can be synthesized from methionine; Tyrosine can be synthesized from phenylalanine.
Essential amino acids
They are obtained from the diet; The body does not contain the enzymes to produce them; Valine is an example of one.
Growing child nitrogen balance
A growing child excretes nitrogen (urea) in urine and is in positive nitrogen balance.
Proteins
Are the body's main source of nitrogen.
All proteins
Contain an amino group and a carboxyl group.
Correct statements about proteins
Proteins have many functions (growth, enzymes, hormones, antibodies, energy, pH); Tertiary structure by R-group interactions; Heat/acid/salt/alkali cause denaturation; Proteins are joined by peptide bonds.
Nitrogen balance equation
Subtracting 2 accounts for nitrogen lost in skin cells and feces.
Transamination
Transfers amino group, used in nonessential AA synthesis, and converts glutamate to alanine.
Function and structure of proteins
Function dictates a protein's structure.
Phenylketonuria (PKU)
Treatment: low-phenylalanine diet; Toxic byproducts cause severe retardation; Cannot synthesize tyrosine.