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what is osmoregulation
the process of maintaining a stable internal balance of water and solutes
water movement across membranes occurs by:
osmosis
many patient conditions are caused by what
altered ion balance
what do depolarization and repolarization underlie
nerve impulses, heartbeat, and muscle contraction
resting membrane potential
Difference of electrical potential inside a cell vs outside a cell
depolarization
The process in which the electrical charge across a cell membrane becomes less negative (or more positive) than it’s resting state
Repolarization:
The process by which a cell membrane returns to its resting negative charge after a nerve or muscle impulse (action potential) has
passed
the inside of a resting cell is more positive or negative than the outside?
more negative
the Na+/K+ pump moves how many in/out
3Na+ out, 2K+ in
K+ is the major ion responsible for what
resting membrane potential
what is neuron resting potential
-70 mV
depolarization makes the membrane less negative or less positive
less negative
repolarization returns the membrane to what
it’s resting negative charge
rapid depolarization is caused by what
fast Na+ influx
repolarization is caused by what
K+ influx
contraction and cardiac plateau phase require what
cardiac contraction strength
in neurons, depolarization opens which channels?
voltage-gated K+ channels
during repolarization what moves out of the cell
K+
hyponatremia many cause what
confusion or seizures
hyperkalemia causes which waves to peak
T waves
phase 0 ventricular AP is cause by :
Na+ influx
phase 2 plateau is caused by:
Ca2+ influx
phase 3 repolarization is caused by:
K+ efflux
QRS represents what
ventricular depolarization
T waves represents what
ventricular repolarization
hypokalemia causes:
flattened T waves and U waves
skeletal muscle depolarizes when what enters
Na+
Ca2+ binds to what to trigger contraction
troponin
Ca2+ must be pumped back to the SR for what
relaxation
hypocalcemia may cause what
Chvostek or trousseau signs
neuromuscular blockers prevent what from binding
Ach
all excitable cells use __ for depolarization and _ for repolarization
Na+ and K+