3. Esophageal Carcinoma

What is this preparation called ?

Esophageal Carcinoma

What organ is this?

Esophagus

Describe the preparation

There is a flat elevated mass in the center — this is the adenocarcinoma

Its at the distal 1/3 of the esophagus = Adenocarcinoma

What causes the adenocarcinoma?

Usually a result of Barrett Esophagus or GERD

What are risk factors of GERD?

• Smoking

• Caffeine

• Alcohol

• Obesity

What are the most common types of tumors in the esophagus?

1. Esophageal Adenocarcinoma (5%)

2. Esophageal Squamous Cell Carcinoma (95%)

What are the predispositions for squamous cell carcinoma ?

• Tobacco use

• HPV

• TOO Hot beverages

• Alpha toxins

What type of tumor is this Esophageal adenocarcinoma?

A malignant tumor

Malignant vs. Benign tumors?

• Malignant

  • Invades / destroys surrounding tissue

  • can metastasize

  • not easily removed surgically

• Benign

  • Remains localized

  • does not metastasize

  • easily removed surgically

Which cells are the ones effected in adenocarcinoma and squamous cell carcinoma?

• Adenocarcinoma: Epithelial lining of the glands and the ducts (Epithelial Origin)

• Squamous Cell: stratified squamous epithelium effects (Epithelial Origin)