* Fertile offspring denotes that they can, in turn, also inbreed and pass on their genes
* If members of two closely related species do interbreed and produce offspring, the **hybrids** will be infertile/ sterile
* This is because both parents have **different numbers of chromosomes**
* Even if the number of chromosomes happen to be the same, the DNA is usually too different and so fertilisation of gametes is not possible