Blood protozoa

Exoerythrocytic cycle

asexual cycle of malaria which occurs in liver cells

Erythrocytic cycle

asexual cycle occuring within RBC’s

what is the earliest morphological stage of malaria

ring forms

Immature schizont

beginning stage of the developed asexual sporzoa trophozoite

Mature Schizont

fully developed stage of the asexual sporozoa troph, characteristic presence of mature merozoites

Schizogony

asexual multiplication within RBCs resulting in merozoites

Merozoite

• contents of fully developed stage of asexual sporozoa trophozoite

• produced in both liver ad RBCs

• capable of infecting other RBCs

sporogony

• stage of the sexual cycle occurring in the mosquito

• result in the production of infective sporozoites

Sporozoites

the infective stage of malaria which develops in the mosquito and is transmitted during a blood meal

Paroxysm correlates with fever which corresponds with…

merozoites and toxic waste byproducts from infected RBCs

Plasmodium vivax has the vector

female anopheles

plasmodium viax has what happen to RBCs

• enlarge RBCs

• schuffners dots

Which form of malaria is ameboid in troph form

Plasmodium vivax

What kind of RBCs does P. vivax like to infect

young RBCs

What kind of RBCs does Plasmodium ovale like to infect?

young cells

What changes in the RBCs are seen with P. ovale infection

• cells get large

• fimbriated edges

• schuffners dots at the beginning of infection

How many schizonts are held in a P.vivax merozoite

12-24

How many schizonts are held in a P.ovale merozoite

8

What kind of RBCs do plasmodium malariae like to infect

Old RBCs

A mature schizont of P. malariae contain how many merozoites

6-12

What changes are seen in RBCs infected with P. mlariae

• bands across the cell

• thick ring and large nucleus in the RBC

P. falciparum tend to infect what kind of RBC

ANY

What changes are seen in the RBC after P. falciprum infection

Mauers dots

What shape are the gametocytes for P. falciprum

crescent shape

Which malaria is associated with black water fever

P. falciprum

What is the stain for malaria

Giemsa

babesia microti vector

Ticks

Babesia mciroti infect RBCs in what way that ids different than malaria

2-4 rings per RBC

In Marthas vineyard you are most likely to catch

Babesia

Amastigote

Oval, nonflagellated morphological form

Promastigote

Long, slender hemoflagellate morphological form containing a free flagellum

Epimastigote

Long, spindle shaped hemoflagellate morphological form equipped with a free flagellum and an undulating membrane that extends one half of the body length

Trypomastigote

• Long and slender to stubby hemoflaggellate form

• typically a C or U shape

• full body length of undulating membrane

Vector of Leishmania braziliensis

Sandfly

What are health issues that can arise from infection of Leishmania braziliensis

Large ulcers of the oral or nasal cavity and secondary bacterial infections

Leishmania braziliensis diagnostic stage

amastigotes

What is the disease associated with Leishmania braziliensis

New world leishmaniasis

What is the vector for leishmania donovni

sand fly

What is the disease associated with leishmania donovni

Kala-azar

What is the diaagnosis stage of leishmania donovni

Amastigotes

leishmania donovni is most likely to invade and multiply in the

liver and spleen

What is the vector of Leishmania tropica

Sandfly

What disease is associated with the Leishmania tropica complex

Oriental boil or cutaneous leishmaniasis

What is the diagnosis stage of Leishmania tropica

Amastigotes

What disease is associated with Trypanosoma brucei gambiense

West African sleeping sickness

What is the vector for Trypanosoma brucei gambiense

Tsetse fly

Trypanosoma brucei gambiense is associated with

Winterbotoms sign (lymph node enlargements)

The diagnosis stage of Trypanosoma brucei gambiense

Trypomastigote

What disease is associated with Trypanosoma brucei rhodesiense

East African sleeping sickness

Trypanosoma brucei rhodesiense vector is

Tsetse fly

Trypanosoma brucei rhodesiense causes

rigors ± winters bottom sign

no lymphoadenopathy

CNS involvement early on

Trypanosoma brucei rhodesiense is diagnostic ing what stage

Trypomastigotes

What disease is associated with Trypanosoma cruzi

chagas disease

What is the vector for Trypanosoma cruzi

Reduvid bug

T. cruzi spreads how

vector defecating on the wound after taking blood meal

What does T. cuzi cause

erythromatous nodule and developing edema and cnjunctivitis

What does chronic chagas disease cause

• myocarditis

• megacolon/esophagous

• hepatosplenomegaly

What is the diagnostic form of Trypanosomas cruzi

Trypomastigotes

P. vivax troph

P. vivax schizonts

P. ovale

P. malariae

P. falciprum

Babesia microti

Trypanosoma brucei gambiense

Trypanosoma brucei rhodesiense

Trypanosomas cruzi