Cell junctions(ECM)

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9 Terms

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Proteoglycans

Cell-ECM interactions and signaling

Glycoproteins containing covalently linked specialized polysaccharide chains

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Collagen

Tissue strength

Several forms, including cross-linked fibers and sheets

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Multiadhesive proteins

Cellmigration/Development

Several proteins contain binding sites for ECM molecules and integrins

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Tight Junction

Septic Junction prevents passage of things through cell gap. 

Transmembrane proteins: Claudins, occludins

Cytoskeletal Attachment: actin

Intracellular proteins:

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Adheren Junction

Connect all membranes through actin filaments(support like lamins).

Transmembrane Protein: Classic Cadherins(E - Cadherins)

Cytoskeletal Attachment: Actin

Intracellular Linker Proteins: Catenins, alpha-actinin

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Desmosome Junction

Transmembrane Protein: Desmosomal Cadherins(desmogleins & desmocollins)

Cytoskeletal Attachment: Intermediate Filaments

Intracellular Proteins: plakoglobin, desmoplakin

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GAP junction

Cell to cell channels made of connexons(hexamer of connexins)

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Integrin

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Hemidesmosome