Naloxone (Narcan) Details

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Last updated 12:23 AM on 7/6/26
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10 Terms

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Class

Opioid Antagonist

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Action

Competitive antagonist, occupies the bonding site for opioids preventing interaction

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Indications

1) Suspected opioid overdose with coma and respiratory depressions (RR <12)

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Contraindications

1) Neonate Overdose

2) Allergy

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Pharmacokinetics

Onset: 3-5 minutes

Peak: 15 minutes

Duration: 30 Minutes

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Side Effects

Irritability, Nausea, Opiate Withdrawal

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Precautions

aggression when regaining consciousness. Focus on respiratory drive. Repeat dosing is likely, opiates will likely outlast naloxone

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Routes

IN, Auto-Injector

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Dosage (Per Maine Protocol)

0.5 mg IN every 2 minutes alternating nostrils until return of spontaneous respirations >12

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Protocol Referenced

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