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True-Breeding
every allele is homozygous
Coding Sequence Mutations
affects which amino acid is translated from the gene
Regulatory Mutation
genetic changes in non-coding DNA regions that control when, where, and how much of a protein is made
Genotype
the complete set of genetic material or specific allele combinations an organism inherits from its parents
Phenotype
the physical expression of an organism’s genes
Dominant Allele
hides a recessive allele and shows its trait even if you only have one copy
Recessive Allele
only shown if you get two copies of it
Wild-Type Allele
the standard, most common version of a gene found naturally in a population
Complete Dominance
the dominant allele completely covers up the recessive allele
Incomplete Dominance
the two alleles blend to make a new middle trait
Independent Assortment
random mixing of maternal and paternal chromosomes during meiosis, meaning the allele a gamete receives for one gene does not influence the allele received for another
Punnet Square
represents all the possible gametes that could unite from a cross
Unlinked Genes
genes that segregate independently during cell division (meiosis) and have an equal chance of being inherited in any combination
Linked Genes
genes located close together on the same chromosome that tend to be inherited together, exceptions being when crossing over separates them
Pulmonary Circuit
the path that moves oxygen-poor blood from the right side of the heart to the lungs, and returns oxygen-rich blood back to the left side of the heart
Systemic Circuit
the part of the cardiovascular system that carries oxygen-rich blood from the left side of the heart to the rest of the body, delivers oxygen and nutrients to tissues, and returns waste-carrying, oxygen-poor blood back to the right side of the heart
Perfusion
the delivery of oxygen-rich blood to cells and the removal of waste from cells
Bulk Flow
the movement of fluids and their dissolved substances together in one direction
Diffusion
the net movement of particles from a region of higher concentration to a region of lower concentration
Where does the blood enter the right side of the heart from?
superior vena cava and the inferior vena cava
Where is blood going at its lowest pressure and lowest oxygen content?
Right Atrium
What prevents blood from traveling backwards?
Heart Valves
Heart Cells
very special cells that are coordinated by nerve bundles firing
Right Ventricle
pumps blood to the lungs
Pulmonary Artery
carries the blood from the right ventricle to the lungs
Capillaries
the smallest blood vessels in the body, measuring just 5 to 10 micrometers in width, and they connect small arteries to small veins to exchange oxygen, nutrients, and waste with body tissues.
Partial Pressure
the pressure it would be if we took away all the other gasses and kept the same volume
Alveoli
air sacks inside lungs
Hemoglobin
an iron-rich protein in red blood cells that transports oxygen from the lungs to the body's tissues, brings carbon dioxide back to the lungs, and gives blood its red color
Where does the most oxygen-rich blood enter?
Left Atrium
Left Ventricle
pumps blood from the heart to capillaries all over the body
Hypothalamus
responds to stimuli to keep the body in homeostasis
Homeostasis
normal levels of body systems
Neurotransmitters
the body’s chemical messengers that nerve cells use to talk to each other and to other target cells like muscles
What does CO2 do in Blood?
dissolves in blood, lowers blood pH, converted to bicarbonate
What does O2 do in Blood?
binds to hemoglobin in red blood cells
Diaphragm
increases lung capacity using negative pressure breathing
Negative Pressure Breathing
the natural process where your chest muscles and diaphragm expand your chest cavity to lower the pressure inside your lungs below the outside air pressure, which pulls air in.
Nerves
bundles of neurons
Action Potentials
electric signal sent via nerves that can be measured as voltage inside a neuron
Dendrites
Branching parts of the neuron that receive incoming signals.
Membrane Potential
charge inside the neuron
Hyperpolarization
a shift in the cell's membrane potential that makes the interior more negative, raising the threshold required to fire an action potential; driven by the closing of sodium channels and the slow, delayed closing of potassium channels
Schwann Cells
specialized glial cells in the peripheral nervous system that form myelin sheaths, speed up nerve signals, and help repair damaged nerves
Glial Cells
non-neuronal support cells in the nervous system that include astrocytes, microglia, and oligodendrocytes
Sensory Neurons
sense different inputs from the outside world; the beginning of an action potential is controlled by sensation rather than voltage
Interneurons
specialized nerve cells that connect sensory and motor neurons, process information, and coordinate body responses
Motor Neurons
specialized nerve cells that transmit electrical signals from the brain and spinal cord to muscles and glands, enabling voluntary and involuntary movements
Neurosecretory Cells
specialized neurons within the hypothalamus that translate nerve signals into hormonal messages
Synapse
occurs at the end of one neuron’s axon and allows it to communicate with another nearby neuron
Soma
cell body of a neuron that contains the nucleus
Axon
long cable-like extension that transmits the action potential
Voltage Gates
specialized proteins that open or close in response to changes in cell membrane voltage, driving electrical signals like sodium, potassium, and calcium actions
Myelin
layers of specialized cell membrane that wrap around axons
Nodes of Ranvier
the spaces between myelin sheaths
Is Na+ concentration inside or outside of the cell?
outside
Is K+ concentration inside or outside of the cell?
inside
Self
originated from the first cell of an embryo, or a single-celled organism
Non-Self
cells or viruses that did not originate from the host cells but are taking the host’s resources
Skin
wall against pathogens
Mucus
slows down bacteria and viruses
Phagocytosis
“eating” bacterial pathogens
Mast Cells
sound the alarm when pathogens enter by releasing histamine from granules to begin the immune response
Macrophages
eat bacterial pathogens and recognize them via receptors on their outer membrane that recognize many common microorganism surface proteins
Cytokines
small proteins released by macrophages and T-cells that trigger inflammation and cause fever
T-Cells
recognize antigens presented on infected cells to induce apoptosis
B-Cells
produce antibodies that bind to pathogens and alert other white blood cells
MHC Class I Complex
presents bits of antigen on the cell surface
Bone Marrow
provides an environment for self-renewal and replication of stem cells
Lymphatic System
vital network of organs, vessels, and tissues that move lymph fluid back into the bloodstream, fight infections, and balance body fluids
Where are antibodies produced?
spleen and lymph nodes
Autoimmune
immune system attacking the host