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Hydrophobic (nonpolar) molecules like hydrocarbons can ____
dissolve in the lipid bilayer and pass through the mmebrane rapidly
Polar molecules like sugars ____
do not cross the membrane easily
transport proteins function
allow passage of hydrophilic substances across the membrane
Passive transport
diffusion of a substance across a membrane with no energy
Diffusion
tendency for molecules to spread out evenly into the available space
molecules move from ___ to ___ concentration
high, low
Dynamic equilibrium
many molecules cross the membrane in opposite directions, keeping the gradient even
Substances diffuse down(with) their ____
concentration gradient
concentration gradient
the region along which the density of a chemical substance decreases
Does any work need to be done to move substances down the concentration gradient
no
Why is the diffusion of a substance across a biological membrane passive transport
it requires no energy
Osmosis
diffusion of water across a selectively permeable membrane
Water diffuses across a membrane from the region of ___ solute concentration to the region of ____ solute concentration until it is ____
lower, higher, equal on both sides
Isotonic solution
solute concentration is teh same as the region it is being compared to
water movement in isotonic solution
no net water movement across the membrane
Hypertonic solution
Solute concentration is greater than the region it is being compared to
water movement in hypertonic solution
out of the cell
Hypotonic solution
solute concentration is less than the region it is being compared to
water movement in a hypotonic solution
water moves into the cell
Best environment for animal cell
Isotonic
Best environment for plant cell
Hypotonic
Osmoregulation
the control of solute concentrations and water balance. needed to survive in hyper or hypotonic environments
Paramecium
hypertonic to its pond water environment, has a contractile vacuole that acts as a pump
facilitated diffusion
passive transport aided by proteins
transport proteins function
speed up passive movement of molecules across the plasma membran
channel and carrier protein function
provide help to move a specific molecule or ion across the mmebrane
channel protein examples
aquaporins: facilitated diffusion of water
Ion channels that open or close in response to a stimulus (gated channels)
Active transport
uses energy to move solutes against their gradients
Active transport moves substances ___ their concentration gradients
against
Active transport requires ___ in the form of ____
energy, ATP (adenosine triphosphate)
Who performs active transport
specific proteins embedded in the membranes
Sodium potassium pump
Exchanges ATP so sodium ions can leave the cytoplasm. Potassium ions release a phosphate group to be allowed into the cytoplasm
Proton pump
Maintains voltage across the membrane.
Hydrogen ions pay ATP to use the proton pump that moves them to the positive area of the extracellular fluid from the cytoplasm
Bulk transport
Movement of large molecules like polysaccharides and proteins across the membrane requiring energy
Exocytosis
transport vesicles migrate to the membrane, fuse with it, and release their contents
endocytosis
the cell takes in macromolecules by forming vesicles from the plasma membrane. Reversal of exocytosis
Three types of endocytosis
phagocytosis, pinocytosis, receptor-mediated endocytosis
Phagocytosis
Cellular eating
A cell engulfs a particle in a vacuole, which fuses with a lysosome to digest the particle
Pinocytosis
Cellular drinking
Molecules are taken up when extracellular fluid is “gulped” into tiny vesicles
Receptor-mediated endocytosis
Binding of ligands to receptors triggers vesicle formation.
ligand definition
any molecule that binds specifically to a receptor site of another molecule