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delirium is acute, dementia is progressive
what is the difference between delirium and dementia?
hemolysis
what does the H in HELLP stand for?
elevated liver enzymes
what does the EL in HELLP stand for?
low platelets
what does the LP in HELLP stand for?
acute tubular necrosis (ATN)
primarily caused by prolonged ischemia or nephrotoxin exposure
prerenal AKI
most common type of AKI that occurs d/t affected renal blood flow & perfusion
ex: hypotension, nephrotoxins, burns, surgery, HF
intrarenal AKI
type of AKI that occurs d/t acute damage to renal tissue and nephrons
ex: acute glomerulonephritis, prolonged HTN, nephrotoxins, sepsis, rhabdomyolysis
postrenal AKI
type of AKI that occurs d/t prevention of kidney outflow
ex: BPH, calculi, cancers, neurogenic bladder
maintenance phase of AKI
phase of AKI:
fall in GFR
AKN
oliguria
azotemia
uremia
recovery phase of AKI
phase of AKI:
cell repair & regeneration
GFR returns to normal
diuresis
chronic kidney disease (CKD)
progressive, irreversible decline in renal function
RAAS → HTN → proteinuria → glomerulosclerosis
causes: diabetes, HTN, chronic glomerulonephritis, infections, drugs/toxins
glomerulonephritis (nephrotic syndrome)
proteinuria → increased LDL production/clearance → renal failure → increased Na/H2O retention → HTN & edema
sodium, calcium
what 2 electrolytes are LOW in patients with CKD?
potassium, phosphorus
what 2 electrolytes are HIGH in patients with CKD?
hyperparaythyroidism
what secondary condition commonly occurs in patients with CKD receiving dialysis?
creatinine clearance
rate at which creatinine is excreted from blood by kidney
24 hour urine collection which is the best indicator of overall renal function
normal: 85-105 mL/min
albumin
protein needed to maintain growth & repair tissues’
may be low in kidney disease, liver disease, malnutrition, dialysis pt, etc.
normal: 3.5-5 g/dL