1. Infectious agent
2. Reservoir (pathogen lives and replicates: food, animals, humans, surfaces)
3. Portal of exit (how the pathogen leaves the reservoir: sneezing, coughing, breathing, open wounds, excretory system)
4. Mode of transmission
5. Portal of entry (inhalation, ingestion, absorption)
6. Susceptible host (ppl w/ autoimmune disorders, babies, elderly, specific jobs w/ more exposure)