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alopecia
absence of hair
hyperpigmentation
excessive coloration of the skin caused by increased deposition of melanin
erythema
redness of the skin; related to vasodilation or free hemorrhage
pruritus
itchy
papule
small solid elevation of the skin
plaque
solid elevation of the skin that is >1cm in diameter and flat topped
pustule
small circumscribed elevation of skin filled with pus that is
abscess
circumscribed elevation of the skin filled with pus that is >1cm in diameter
epidermal collarette
pustule rupture that leaves a rim of dead keratin
nodule
small, circumscribed solid elevation extending into deeper layers of the skin
tumor
if a nodule turns out to have neoplastic cells it is now called what
seborrhea
conditions characterized by increased epidermal turnover and changes in the quantity or quality of sebum
seborrhea oleosa is ___
greasy
seborrhea sicca is ___
dry
lichenification
thickening of the skin characterized by exaggeration of superficial markings; characteristic of chronic dermatitis
hyperkeratosis
increases in the thickness of the horny layer of the skin
what is the name of the horny layer of the skin
stratum corneum
colonization
increased numbers of bacteria or yeast on the surface of the skin
crust
dried exudate on the skin consisting of serum, pus, blood, scales, meds, hair
dermatophyte
fungus that invades keratinized tissues (hair, nails, hooves, etc)
epidermal turnover time
the length of time for epidermal cells to move from the basal cell layer to the stratum corneum and slough off
what is the normal epidermal turnover time
21 days
ulcer
break in the continuity of the epidermis with exposure of the underlying dermis
erosion
if a break in the continuity of epidermis is not through the epidermis it is known as this
scar
area of fibrous tissue that has replaced damaged dermis or subcutaneous tissue
scale
accumulation of loose fragments of the horny layer of the skin (dandruff)
keratolytic
agent that helps remove excessive stratum corneum
keratoplastic
agent that helps normalize epidermal turnover
excoriation
abrasion of a portion of the skin caused by scratching
pyoderma
bacterial infection involving the skin that is classified as primary or secondary; classified according to depth of infection
pyodermas should always be considered a ____ clinical manifestation of an underlying problem
secondary
infection that doesn't penetrate the stratum corneum (top layer of epidermis); bacterial involvement is secondary
surface pyoderma
what is the common name for acute moist dermatitis
hot spot
acute moist dermatitis
rapid onset of a painful and erythematous lesion that can be swollen, alopecic, and exudative; treatment is to clip and clean area making sure to dry it as well as treat with anti-inflammatories and maybe antibiotics
skin fold pyoderma
produced by friction and minor trauma; moisture and glandular secretions provide a prime environment; occur in any breed type with anatomical defects (brachycephalics, shar pei)
superficial pyoderma
infection of the skin involving the hair follicles and the adjacent epidermi
____ ____ and impetigo are common terms for superficial pustular dermatitis
puppy pyoderma
superficial pustular dermatitis
characterized by small, nonfollicular pustules and papules, and crusts limited to inguinal and axillary skin; not painful or pruritic
common name for dermatopylosis
lumpy wool
dermatophylosis
bacteria on skin and fleece becomes an active infection when the animal is exposed to excessive moisture
folliculitis
infection of the hair follicles caused by yeast or bacteria colonizing the follicle the can present in any age, breed, or sex of dog; clinical signs are papules and pustules, hair loss creating moth eaten appearance, epidermal collarette, bulls eye lesion
after diagnosing folliculitis the patient needs to be on antibiotics for ____ past resolution of clinical signs as well using topical therapy
1 week
bacterial infection that breaks through hair follicles to produce furunculosis and cellulitis; common in dogs but rare in cats; lesions are often pruritic or painful and have draining tracts
deep pyoderma
another name for furunculosis
boil
when treating a deep pyoderma systemic antibiotics need to be adminisered for ____ past resolution of clinicals signs as well as using topical therpay
2 weeks
when treating this deep pyoderma try to reduce weight, padded environment; poor prognosis
pressure point
when treating this deep pyoderma use foot soaks, confine to minimize trauma; surgery may be required
interdigital
for this type of deep pyoderma clip the dog and bathe frequently (whirlpools +/- bleach solution)
generalized
methicillin resistant staphylococcus
gram positive bacteria that have developed resistance to the antibiotic methicillin and other beta-lactam antibiotics including penicillins, cephalosporins, and carbapenems; confirmed by culture and sensitivity
allergies
altered state of immune reactivity; hypersensitivity; indicated by chewing/scratching/licking at skin, rubbing against surfaces, shaking head, areas of hair loss
atopic dermatitis
genetically predisposed inflammatory and pruritic allergic skin disease with characteristic clinical features associated with IgE antibodies most commonly directed against environmental allergens; involves the face, ears, feet under the arms and back legs
atopic dermatitis can have ____ signs that are not common in dogs like sneezing, runny nose, and eyes
respiratory
what is considered the gold standard therapy for atopic dermatitis; process of gradually increasing the amount of a substance given to an individual that is allergic
immunotherapy
feline atopy
generalized pruritus of the head and neck in cats that start seasonally and progress; can show respiratory signs such as sneezing and conjunctivitis as well as clinical signs like symmetrical alopecia, eosinophilic ulcers, miliary dermatitis, and eosinophilic plaques
food allergies
allergic reaction to an ingredient in a dog's diet (protein) om which you can see GI signs, intense pruritus
to test for a food allergy a ___ ___ needs to be conducted for 8-10 weeks and if a positive response is seen the pet is challenged with their original diet
food trial
this class of drug is not as helpful in dealing with allergies in animals as it is in people; needs to be given on a regular basis and can cause drowsiness
antihistamine
drug that block the release of inflammatory molecules; expensive; side effects are GI signs and gingival hyperplasia; cyclosporin
atopica
a janus kinase inhibitor drug that blocks a protein that is integral to the signaling pathway resulting in pruritus and inflammation; labeled for dogs only currently; one cost for all sizes; GI signs side effect; not recommended for cancer patients
apoquel
a caninized monoclonal antibody that targets the cytokine interleukin 31 that blocks the itch signal to the brain; for dogs only; expensive and must be given in the clinic; per zoetis is safe for all dogs
cytopoint
one cytopoint injection is said to last 4-8 weeks but most need redosed by ___ weeks
4
allergic contact dermatitis
type IV hypersensitivity that usually requires long term exposure; substances implicated to cause it are plant pollens, resins like ragweed and poison ivy, wool, carpet dyes, wood finishes/polishes
irritant dermatitis
more common than allergic contact dermatitis; substance that physically damages the skin and may occur after single contact
otitis externa
acute or chronic inflammatory disease of the external ear canal
dermatophytosis
contagious and zoonotic spread by direct contact and fomites; infections of the hair shaft and follicle; three species of fungi that cause majority of infections; clinical signs are pruritus, alopecia, broken off hair, erythema, papules, crusts, seborrhea
deomodicosis
demodex mites are transmitted from the dam to pups early in in life; excessive proliferation of mites leads to clinical disease
sarcoptes scabiei
superficial burrowing skin mite that secretes allergenic substances that elicit an intensely pruritic hypersensitivity reaction; zoonotic
notoedres cati
superficial sarcoptic mite known as feline scabies; rare; extremely pruritic, dry, crusted lesions; peripheral lymphadenomegaly; highly contagious
fleas
small, wingless, blood sucking parasite that thrives in warm temperatures; most common species in ctenocephalides felis
flea allergy dermatitis
common in dogs and cats that are sensitized to flea bites; pruritic lesions that can lead to alopecia, erythema, pyoderma, hyperpigmentation, and/or lichenification
Common name for Cheyletiella
walking dandruff
cheyletiella
live on and fur; visit skin only to feed; all stages are parasitic; uncommon but highly contagious; excessive scaling over dorsal midline, minimal pruritus, papular crusting eruptions
pemphigus foliaceus
production of autoantibodies that target proteins binding the cells of the epidermis; most common autoimmune disease in dogs and cats; primary lesions are superficial pustules that rupture easily; occur on bridge of nose, around eyes, and on ear pinnae
what is the hallmark finding on cytology of pemphigus foliaceus along with nondegerated neutrophils and eosinophils
acanthocytes
pemphigus erythematosus
benign form of pemphigus foliaceus or crossover between pemphigus and lupus; uncommon in cats but commonly occurs in dogs (german shepherds, collies, shelties); occurs on bridge of nose, around eyes, and pinnae
animals with pemphigus erythematosus and/pr discoid lupus erythematosis need to avoid too much of what
sunlight
discoid lupus erythematosis
benign variation of lupus erythematosus; common in dogs but rare in cats; nasal depigmentation, erythema, scaling, erosions, ulcerations, crusting; lips, bridge of nose, around eyes, pinnae, distal limbs, genitalia
lupoid onychodystrophy
lupus like disease causing loss of nails; highest incidence in young adult and middle aged dogs; acute onset initially affecting only a few claws; painful; partial regrowth occurs and nails are misshapen, soft or brittle, discolored, friable
patients with lupoid onychodystrophy may need to undergo a therapeutic ___ procedure if they are severely painful
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