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The Endomembrane System
Manufactures, ships, and Recycled/used
The Endomembrane System step 1
protein enters ER
The Endomembrane System step 2
proteins exits the ER
The Endomembrane System step 3
protein enters Golgi apparatus
The Endomembrane System step 4
protein exits Golgi apparatus
The Endomembrane System step 5
protein is secreted from the cell
What Happens Inside the Golgi Apparatus?
Proteins are transported in vesicles
how are proteins transported
budding off the ER
what does the vesical fuse with
cis face
what does Proteins transported into the vesicle dump in the Golgi Apparatus
cargo “cells'“
New cisternae form at
cis face
Old cisternae break off from the
trans face
what are the old cisternae replaced by
cisternae behind them
Different cisternae contain different
enzymes
Proteins are modified as they
move through
Each protein that comes out of the Golgi apparatus has
molecular tag
molecular tags place proteins with
particular type of transport vesicle
Each type of transport vesicle also has a tag that allows
it to be transported to the correct destination
Large molecules must be digested by ? before their monomers can be used by the cell
lysosomes
3 pathways of lysosomes
Receptor mediated, Phagocytosis, Autophagy
Receptor-mediated endocytosis
Particles bind to receptors on the plasma membrane (based on the particles)
in what are Plasma membrane pinches off to form a vesicle
Receptor-mediated endocytosis
what Recycling Material in the Lysosome uses Vesicle fuses with an early endosome and proton pumps lower pH; receptor
Receptor-mediated endocytosis
Vesicles matures into a lysosome in
Receptor-mediated endocytosis
Phagocytosis (“eat-cell-act”)
Plasma membrane engulfs a smaller cell or food particle
what forms because of Phagocytosis
phagosome
what do phagosome fuse with
lysosome
Phagocytosis Materials are taken
in and digested
Autophagy (“same-eating”)
Fuses with a lysosome for digestion
Autophagosome forms
around structure inside the cell