a non-living, physical factor that can influence an organism or ecosystem, e.g. temperature, sunlight, pH, salinity or precipitation.
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ABO system
a system of four basic blood types (A, AB, B and O), based on the presence or absence of specific inherited antigens.
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Absorption spectrum
a graph showing the relative absorbance of different wavelengths of light by a pigment.
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Accessory pigments
light-absorbing compounds that trap light energy and channel it to chlorophyll a, the primary pigment, which initiates the reactions of photosynthesis.
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Accuracy
how close to the true value a result is.
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Acetylcholine (ACh)
a neurotransmitter that functions in both the central and peripheral nervous systems.
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Acrosome
sac at head of sperm containing protease enzymes.
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Actin
a thin protein that forms (together with myosin) the contractile filaments of muscle cells; contains binding sites for the myosin heads.
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Action potential
the potential difference produced across the plasma membrane of the nerve cell when stimulated, reversing the resting potential from about −70mV to about +40mV.
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Action spectrum
range of wavelengths of light within which a process like photosynthesis takes place.
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Activated B-cell
B-cells absorb an antigen and present pieces of it on their surface via a major histocompatibility complex (MHC); helper T-cells then recognize the antigens via the MHC and activate the B-cells, resulting in B-cell differentiation into memory B-cells or plasma cells.
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Activation energy
energy required by a substrate molecule before it can undergo a chemical change.
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Active site
region of an enzyme molecule where the substrate molecule binds and catalysis occurs.
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Active transport
movement of particles from lower to higher concentration, using energy from ATP that has been created during respiration. Movement is through carrier proteins.
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Adaptive immune system
responds in a specific way to particular pathogens and builds up a memory of pathogens encountered, so the immune response becomes more effective.
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Adaptive radiation
the diversification of an ancestral species into new species, characterized by great ecological and morphological diversity, filling different ecological niches.
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Adenine
a purine nitrogenous base, found in the coenzymes ATP and NADP, and in nucleic acids (DNA and RNA), that pairs with thymine.
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Adenosine diphosphate (ADP)
a nucleotide, present in every living cell, made of adenosine and two phosphate groups bonded in a linear sequence; it is important in energy-transfer reactions of metabolism.
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Adenosine triphosphate (ATP)
a nucleotide, present in every living cell, formed in photosynthesis and respiration from ADP and Pi; it functions in metabolism as a common intermediate between energy-requiring and energy-yielding reactions.
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Adenylyl cyclase/adenylate cyclase
enzyme that catalyses the formation of cAMP from ATP.
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Adhesion
the force by which individual molecules stick to surrounding materials and surfaces.
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Adipose tissue
a tissue found beneath the skin layer, containing fat cells.
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Aerobic respiration
respiration requiring oxygen, involving the oxidation of glucose to carbon dioxide and water.
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Afforestation
the establishment of forests in an area where there was no previous tree cover.
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Agglutination
process in which red blood cells are clumped together by an antibody.
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Agrochemical
a chemical used in agriculture, such as a pesticide or a fertilizer.
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AIDS (acquired immune deficiency syndrome)
the name used to describe a number of potentially life-threatening infections and illnesses that happen when the immune system has been severely damaged by the HIV virus.
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Albedo
the fraction of solar radiation reflected by a surface or object, often expressed as a percentage.
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Alien species
species that are introduced into an area by human activity.
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Allele
different versions of the same gene occupying a specific locus on a chromosome.
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Allelopathy
chemical inhibition of one plant (or other organism) by another, due to the release of chemicals (allelochemicals) that act as germination or growth inhibitors.
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Allopatric speciation
speciation that occurs when two groups of organisms are spatially separated by a physical or geographic barrier, e.g. mountain ranges and large rivers.
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Allosteric protein
a protein that can exist in multiple conformations (shapes) depending on the binding of a molecule (at a site other than the catalytic site).
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Allosteric regulators
molecules that change the shape and activity of an enzyme by reversibly binding at a site on the enzyme.
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Alpha (α) cell
glucagon-secreting cell of the islets of Langerhans in the pancreas.
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Alternative hypothesis
there is a statistically significant difference between two variables.
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Alternative splicing
process of splicing of exons to produce variants of a protein from a single gene.
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Altruism
behaviour of an animal that benefits another at its own expense. Biologists call a behaviour pattern altruistic if it increases the number of offspring produced by the recipient and decreases that of the altruist.
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Alveolus (plural, alveoli)
air sac in the lung.
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Amphipathic
a molecule that has two different affinities - a polar end that is attracted to water (hydrophilic) and a non-polar end that is repelled by it (hydrophobic).
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Anabolism
the synthesis of complex molecules from simpler molecules including the formation of macromolecules from monomers by condensation reactions.
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Anaerobic respiration
respiration in the absence of oxygen, producing either lactic acid (humans) or ethanol and carbon dioxide (plants and yeast).
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Analogous structure
a feature with a similar function and superficial structural similarity, but different fundamental structure and evolutionary origin.
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Analyse
break down in order to bring out the essential elements or structure.
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Anaphase
stage in nuclear division where chromosomes move away from one another to opposite poles of the cell.
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Annotate
add brief notes to a diagram or graph.
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Antagonistic muscle
a muscle that works as one of a pair: as one muscle contracts, the other muscle relaxes/lengthens. The muscle that is contracting is called the agonist and the muscle that is relaxing/lengthening is called the antagonist.
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Anther
produces pollen, which contains the male gamete.
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Anthropogenic
relating to human activity.
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Antibiotics
chemicals that block processes occurring in bacteria but not in eukaryotic cells.
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Antibody
a protein produced by blood plasma cells derived from B lymphocytes when in the presence of a specific antigen, which then binds with the antigen, aiding its destruction.
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Anticodon
set of three consecutive nucleotides in a tRNA molecule that recognizes, through base pairing, the three-nucleotide codon on a messenger RNA molecule.
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Antigen
a substance (usually glycoproteins or other protein) capable of binding specifically to an antibody. It is recognized by the body as foreign (non-self) and stimulates an immune response.
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Antigenic drift
small changes (caused by mutations) in viral genes that can lead to changes in the surface proteins of a virus, HA (haemagglutinin) and NA (neuraminidase).
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Antigenic shift
an abrupt, major change in an influenza A virus, resulting in new HA (haemagglutinin) and/or new HA and NA (neuraminidase) proteins. Happens when recombination occurs.
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Antigen presentation
process where an antigen is taken into a white blood cell by receptor-mediated endocytosis, digested, complexed with MHC II molecules and then presented on the cell surface membrane for interaction with T-cells.
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Antigen-specific B-cell
lymphocytes that form either antibody-secreting cells or memory B-cells after infection or vaccination.
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Aorta
main artery that carries blood away from the heart to the rest of the body.
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Apoplast pathway
the pathway (e.g. of water) through the non-living part of a cell, e.g. cell walls and spaces between cells.
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Apoptosis
a form of programmed cell death that allows cells that are unneeded or unwanted to be eliminated from an adult or developing organism.
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Aquaporin
a water channel pore (protein) in a membrane.
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Arrested succession (plagioclimax)
an area where human activity has prevented the ecosystem developing a climax community.
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Arteriole
a very small artery.
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Artificial classification
classifying organisms on the basis of few, self-evident features.
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Artificial selection
selection in breeding, carried out deliberately by humans to alter populations.
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Asexual reproduction
reproduction not involving gametes and fertilization.
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Assimilation
uptake of nutrients into cells and the utilization of this material to provide energy and to synthesize new biological molecules.
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Atherosclerosis
deposition of plaque (cholesterol derivative) in the inner wall of blood vessels.
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ATPase
a group of enzymes that catalyze the hydrolysis of a phosphate bond in adenosine triphosphate (ATP) to form adenosine diphosphate (ADP).
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ATP synthase (ATPase)
a complex of integral proteins located in the mitochondrial inner membrane where it catalyses the synthesis of ATP from ADP and phosphate, driven by a flow of protons.
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Atrioventricular node
mass of specialized cardiac muscle cells in the wall of the right atrium.
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Atrioventricular valve
heart valve that opens to allow the passage of blood into a ventricle; it closes to prevent the backflow of blood into the atrium.
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Atrium (plural, atria)
upper chambers of the heart from which blood is passed to the ventricles.
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Autoinducers
a signalling molecule produced and used by bacteria participating in quorum sensing.
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Autonomic nervous system (ANS)
the involuntary nervous system.
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Autophosphorylation
the phosphorylation of a kinase by itself.
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Autosomal gene
gene located on one of the numbered, or non-sex, chromosomes.
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Autotrophic
using external energy sources to synthesize glucose from simple inorganic substances.
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Auxin
plant growth substance, indoleacetic acid, which generally stimulates cell elongation.
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Axon
fibre carrying impulses away from the cell body of a neuron.
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Bacteriophage
a virus that parasitizes bacteria (also known as a phage).
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Baroreceptor
a sensory receptor responding to stretch in the walls of blood vessels to monitor blood pressure.
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Belt transect
all organisms within a band, usually between 0.5m and 1m, are sampled along an environmental gradient.
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Benign tumour
a tumour that tends to grow slowly and does not spread to other parts of the body.
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Beta (β) cell
insulin-secreting cells of the islets of Langerhans in the pancreas.
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Bicuspid valve
atrioventricular valve on the left side of the heart.
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Binary fission
when a cell divides into two daughter cells, typically in asexual reproduction of prokaryotes.
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Binomial system
double names for organisms, in Latin, with the generic name preceding the specific name.
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Bioaccumulation
the build-up of non-biodegradable or slowly biodegradable chemicals in the body.
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Biochemical oxygen demand (BOD)
a measure of the amount of dissolved oxygen required to break down the organic material in a given volume of water through aerobic biological activity.
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Biodiversity
the amount of biological or living diversity per unit area. It includes the concepts of species diversity, habitat diversity and genetic diversity.
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Biological species concept
a species is a group of organisms that can breed and produce fertile offspring.
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Biomagnification
the process by which chemical substances become concentrated in the tissues of organisms at higher trophic levels.
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Biome
groups of ecosystems with similar abiotic conditions and communities, defined by their climate and dominant plant species.
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Biotic factor
a living part of an ecosystem (i.e. part of the community) that can influence an organism or ecosystem.
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Bivalent
a pair of duplicated homologous chromosomes, held together by chiasmata during meiosis.
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Blastocyst
embryo as fluid-filled ball of cells, at the stage of implantation.
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B-lymphocytes (B-cells)
lymphocytes that produce antibodies and are responsible for presenting antigens to T-cells. Once activated, they can mature into plasma cells or memory B-lymphocytes.
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Bohr effect
the decrease in the oxygen affinity of haemoglobin in response to decreased blood pH, resulting from increased carbon dioxide concentration in the blood.