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ADEK
what are the fat soluble vitamins
liver and adipose
where are fat soluble vitamins stored
daily intake
what type of intake must be done for water-soluble vitamins
preformed
what type of vitamin a is from animal products
retinol, retinal, retinoic acid
what are the three types of preformed vitamin a
retinol
what type of vitamin a is for reproduction and growth
retinal
what type of vitamin a is for vision
retinoic acid
what type of vitamin a is for cell differentiation
proformed (carotenoids)
what type of vitamin a is from plant products
lutein and xeanxanthin
what are 2 types of carotenoids that are antioxidants found to protect the eye from UV-induced eye damage
increase
with proformed vitamin A the absorption does what when they are cooked
passive diffusion
what type of diffusion occurs in the duodenum and the jejunum for vitamin a
ARAT and LRAT
what are the two
(crbp-retinol, lrat) CRBP-retinal
what turns retinol into retinoic acid
protein and zinc
what is used to convert retinol into RBP-retinol
900
what is the RDA for men for vitamin a
700
what is the RDA for women for vitamin a
beef liver, sweet potato, spinach
what is the food source of vitamin a
fatty malabsorption
what is the secondary cause of vitamin a deficiencies
premature infants and cystic fibrosis
what are the populations at risk for a vitamin a deficiency
depressed immune system, follicular hyperkeratosis
what are the two major signs of deficiency symptoms
night blindness, xerosis, xerophthalmia and bitot spots
what are the vision issues that come with vitamin a deficiency
preformed (toxicity)
what type of vitamin a toxicity occurs with hyperkeratinosis
teratogenic
what can occur with infants if there is vitamin a toxicity
cholecalciferol
what is the vitamin d animal form
ergocalciferol
what is the plant form a vitamin d
gene expression, increase absorption with the small intestine, increase renal absorption and decrease inflammation
what are the functions of vitamin D
PTH
low blood calcium causes what to be released from the parathyroid gland
hydroxylase
PTH induces what to occur in the kidneys when blood calcium is low
calcitriol
what does hydroxylase activate
calcium binding proteins
calcitriol stimulates the synthesis of what
25-hydroxyvitamin D
what is the best biomarker for assessment
cod liver, trout, salmon and mushrooms
what are the major sources of vitamin D
rickets
what is a vitamin D deficiency in children
osteomalacia
what is the vitamin D deficiency in adults that causes soft and spongy bones
breast fed infants and fatty malabsorption
what are the risks for a vitamin D deficiency
kidney, lung and heart
what can calcify due to a toxicity of vitamin D
alphatocopheral
what is the other name of vitamin E
antioxidants in plasma membrane
what is the function of vitamin E because it donates H to free radicals
C
what vitamin is the key to E
protein kinase C
what does vitamin E inhibit
blood thinner
vitamin E does what to the blood due to the increase prostacyclin production resulting in vasodilation and inhibition of platelet aggregation
vegan and pregnant/lactating women
who is at risk for a vitamin E deficiency
400
how many milligrams are given to prevent migraines
hemolytic anemia
what happens in infants when there is hypovitaminosis E
vitamin K
supplementation of vitamin E can result in inhibition of what other vitamin
phylloquinone
what is vitamin K found in green plants and is the major of vitamin K
menaquinone
what is the vitamin K made by bacteria
carboxylglutamates (calcium binding sites)
what is vitamin K a coenzyme for
clotting and bone production
what is vitamin K's major functions
VII, IX and X
what stages is vitamin K needed for in clotting production
broccoli, dark green and leafy greens
what are the sources of phylloquinone
natto, meat, dairy, eggs
what are the sources of menaquinones
new borns, fat malabsorption, prolonged use of antibiotics
who is at risk for vitamin K deficiency
increased bleeding, poor bone growth
what are the symptoms of a vitamin K deficiency
no
are there any toxicity for vitamin k
ascorbic acid
what is the reduced form of vitamin C
connective tissue, metabolism of folate and tryptophan, absorption of non-heme iron
what is vitamin c required for
iron
what mineral is needed to turn proline or lysin into the hydroxylated forms
90, 75 +35
what is the RDA for men, women and smokers for vitamin C
bell peppers, citrus, broccoli
what are the sources of vitamin C
100
when do cells become saturated for bioavailability
oral
what maximally raises serum levels in small amounts and can cause osmotic diarrhea
oxygen, heat and basic pH
what makes vitamin Ce unstabel
water
vitamin C is easily extracted in water
hemorrhagic signs, hyperkeratosis (of hair follicles), hypochondriasis, hematologic
what are the 4Hs of scurvy
corkscrew hairs and bleeding gums
what are signs of a scurvy deficiency
kidney disease and impaired iron metabolism
what can high doses of vitamin C cause
nonheme
what type of iron absorption is vitamin C involved in