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Sarcomere
Contractile unit of the cell.
Fast Twitch
Skeletal single stimulation, single contraction of a motor unit
Slow Twitch
Cardiac, smooth muscles single contraction of a motor unit
Cross Bridging
Ca++ released by SR bind to tropin this will move tropomyosin and allow cross bridging between actin & myosin
Power Stroke
ADP + P as fuel myosin head grabs G-Actin and slide it to the middle & myosin spins allowing head to reach & pull actin closer (Sarcomere shortens).
Detachment
ATP is consumed; ATP bind myosin head & triggers release of myosin from actin.
Reactivation
ATP is oxidized releasing energy & moves myosin into ‘cocked’/ready position
Parts of a Twitch
Latent Phase, contraction phase, relaxation phase
Latent Phase
Depolarization & repolarization last 2-3 milliseconds
Contraction Phase
Calcium release, cross bridge cycle lasts 30-180ms
Relaxation Phase
10-30ms
Complete/fused Tetanus
High frequency and buid up of Ca++ in the motor untit
Body Recruitment
The stronger the stimuli the more info propriceptors send to the cerebellum to alternates the motor units stimulated
ATP Production
Direct Phosphorylation, Anaerobic Respiration, Aerobic Respiration,
Direct Phosphorylation
ATP is burned and becomes ADP; ADP reacts to Creatine Phosphate and donates P group making it ATP again takes 15 sec.
Anaerobic Respiration
Undergoes Glycolisis, lack oxygen produce 2 ATP per glucose, but lacks oxygen Pyruvic Acid turn to Latic acid
Latic Acid
Only heat muscle, liver, kidneys, can use the term for energy, skeletal muscle builds up and needs to be removed
Smooth Muscle
Found in hollow organs (visceral) no visible striations, arrangement of myofilaments, relies on Extra Cellular Calcium
Extra Cellular Calcium
Calcium attaches Calmodulin
Smooth Muscle Types
Single unit, Multi unit
single Unit
Visceral muscle found in organ innervated by PSNS, contains gap junctions to allow wave like contraction, stress relaxation response, spontaneously contracts contain Varicosities
Varicosities
Nerve endings that release ACh
Multi Unit
Controlled by SNS, motor units produce control, acts like skeletal muscle than NMJ found in skin (arrector pili) and blood vessels (blood flow changes in blood)
Cramps
Painful tetanus caused by Dehydration and a loss of Potassium in the cells due to Aldosterone
Muscle Growth
Cause by adding to the filament GH, and testosterone
Muscle Fatigue
Caused by oxygen debt, muscle need to replenish stores O2 removal lactic acid caused by anaerobic respiration requires movement and plenty of water
Development of Tension
Changes in frequency can be stimulated muscle fibers contraction increased, impulses sent are called wave summation.