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100 vocabulary-style flashcards covering the major concepts, terms, and mechanisms described in the notes on stress and related problems.
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Stress
The generalized or systemic response to a change (stressor), internal or external.
Stressor
Any factor that creates a significant change in the body or environment; may be physical, psychological, or both.
General Adaptation Syndrome (GAS)
Selye’s three-stage response to stress: alarm, resistance, and exhaustion.
Alarm stage
First stage of GAS; the body’s defenses are mobilized by the hypothalamus, SNS, and adrenal glands.
Resistance stage
Second stage of GAS; hormonal levels are elevated and essential body systems operate at peak performance.
Exhaustion stage
Final stage of GAS; the body is unable to respond further or is damaged by the increased demands.
Fight or flight
The immediate, generalized response to a stressor, preparing the body to confront or flee.
Homeostasis
The regulation of internal conditions to maintain a stable state.
Maladaptive
Unhelpful or harmful physiologic or behavioral responses to stress.
Eustress (Positive stress)
Stress that is inspiring and may promote long-term health, motivation, and focus.
Distress (Negative stress)
Unhelpful or harmful stress that can lead to adverse health effects.
Techno-stress (Technostress)
Stress related to the use of information and communication technologies (ICTs).
Smartphone use disorder
A problematic pattern of smartphone use associated with notable stress reactions.
Cortisol
A glucocorticoid hormone released by the adrenal cortex; raises glucose, suppresses certain immune responses.
ACTH (Adrenocorticotropic hormone)
Pituitary hormone that stimulates cortisol release from the adrenal cortex.
CRF (Corticotropin-releasing factor)
Hypothalamic factor that stimulates ACTH release.
Adrenal medulla
Part of the adrenal gland that secretes epinephrine and norepinephrine in response to stress.
Norepinephrine
Catecholamine released from sympathetic nerves; increases arousal and causes vasoconstriction.
Epinephrine (Adrenaline)
Catecholamine that increases heart rate, blood pressure, and bronchodilation.
Aldosterone
Mineralocorticoid from the adrenal cortex; promotes Na+ and water retention, increasing blood volume.
ADH (Antidiuretic hormone, vasopressin)
Posterior pituitary hormone that promotes water reabsorption, increasing blood volume and pressure.
Vasoconstriction
Narrowing of blood vessels, reducing blood flow to certain areas.
Vasodilation
Widening of blood vessels, increasing blood flow to tissues.
Bronchodilation
Dilation of the bronchioles, enhancing ventilation.
Glycogenolysis
Breakdown of glycogen to glucose in the liver.
Gluconeogenesis
Production of glucose from non-carbohydrate sources.
Protein catabolism
Breakdown of proteins into amino acids for energy or gluconeogenesis.
Lipolysis
Breakdown of fats to fatty acids and glycerol for energy.
Hyperglycemia
Elevated blood glucose levels during stress response.
Inflammatory response decrease
Cortisol reduces inflammatory responses, especially early stages.
Immune suppression
Reduction in immune system activity during stress.
Memory impairment
Stress-related disruption of memory formation and recall, especially with glucocorticoids.
Acute renal failure
Kidney failure from prolonged severe vasoconstriction and reduced blood flow.
Stress ulcers
Gastric ulcers that occur under severe stress; can cause bleeding.
Curling ulcer
Stress-related gastric ulcer associated with severe burns.
Stomatitis
Inflammation or ulcers in the mouth linked to stress.
Periodontitis
Inflammation of periodontal tissues; can be stress-related.
Peptic ulcer
Ulcers in the stomach or duodenum associated with stress.
Ulcerative colitis
Chronic inflammatory bowel disease that can be aggravated by stress.
Regional ileitis (Crohn’s disease)
Chronic inflammatory bowel disease often related to stress.
Nausea
Feeling of sickness that can accompany stress.
Diarrhea
Frequent loose stools; can be stress-related.
Herpes simplex
Herpes simplex outbreaks can be triggered or worsened by stress.
Eczema
Dermatitis that may flare with stress.
Acne
Skin condition that can worsen with stress.
Hypertension
Elevated blood pressure associated with stress.
Angina
Chest pain due to reduced blood flow; can be precipitated by stress.
Congestive heart failure
Heart’s reduced pumping ability; stress can worsen symptoms.
Cerebrovascular accident (Stroke)
Acute brain event; stress may precipitate in susceptible individuals.
Cancer
Malignant disease; chronic stress may influence progression or risk.
Infection
Increased susceptibility to infection due to immune suppression.
Autoimmune disorders
Diseases where immune responses attack the body's own tissues; stress can influence activity.
Obesity
Excess body fat associated with chronic stress and coping behaviors.
Multiple sclerosis
Autoimmune CNS disorder; stress may exacerbate symptoms.
Seizures
Abnormal neuronal activity; stress can trigger seizures in susceptible individuals.
Depression
Mood disorder that can be exacerbated by stress.
Tension headache
Headache associated with muscular tension during stress.
Insomnia
Difficulty sleeping due to stress or hyperarousal.
Diabetes mellitus
Metabolic disorder of glucose regulation; stress can worsen control.
Cirrhosis caused by alcohol abuse
Liver cirrhosis linked to alcohol use, which can be worsened by stress.
Posttraumatic stress disorder (PTSD)
Severe stress reaction after trauma; may involve re-experiencing, avoidance, and dissociation.
Re-experiencing (reliving)
Symptoms of PTSD involving reliving the traumatic event.
Avoidance
PTSD symptom of avoiding reminders of the trauma.
Dissociative state
PTSD symptom of emotional detachment or blunting.
Coping strategies
Methods used to manage stress and reduce its impact.
Aerobic exercise
Endurance activity (cycling, swimming, running) that reduces stress and improves circulation.
Blood glucose stability during aerobic exercise
Steady blood glucose levels during aerobic activity due to fat utilization.
Relaxation techniques
Strategies (breathing, progressive relaxation) to reduce stress.
Imagery
Visualization technique used to induce relaxation and coping.
Biofeedback therapy
Technique to gain conscious control of physiological functions.
Music therapy
Use of music to reduce stress and improve well-being.
Art therapy
Use of art activities to cope with stress and express emotions.
Counseling and support services
Professional support to help manage stress and coping.
Lorazepam (Ativan)
Short-acting benzodiazepine used for short-term anxiety relief; caution for side effects.
Sleep hygiene
Practices to improve sleep quality and duration.
Support system
Social support from family, friends, or community that helps manage stress.
Maladaptive coping mechanisms
Unhelpful strategies (e.g., overeating, excessive caffeine, smoking) that worsen stress.
Locus ceruleus
Cluster of norepinephrine-secreting cells in the brainstem that drives rapid stress responses.
Sympathetic nervous system (SNS)
Part of the autonomic nervous system that triggers rapid, involuntary responses to stress.
Central nervous system activation
Stimulation of the brain and spinal cord in response to stress.
Hypothalamus
Brain region that initiates the stress response via CRF and the HPA axis.
Pituitary gland
Gland that releases ACTH in response to CRF.
Adrenal cortex
Outer adrenal gland portion that secretes cortisol and aldosterone.
Corticosteroids
Hormones produced by the adrenal cortex, including cortisol and aldosterone.
Endorphins
Endogenous opioid peptides released during stress that dampen pain.
Ischemia
Reduced blood flow to tissue, potentially causing damage.
Delayed healing
Slower tissue repair due to cortisol and catecholamine effects.
Opportunistic infections
Infections by organisms that are normally nonpathogenic, due to immune suppression.
Lymphoid tissue atrophy
Shrinkage of lymphoid tissue with prolonged cortisol exposure.
Glucocorticoids
Class of steroid hormones (including cortisol) that regulate metabolism and suppress inflammation.
WBC suppression
Reduction in white blood cell numbers or function during stress.
Memory disruption
Stress can disrupt memory formation and retrieval through hormonal effects.
Recovery to normal status
Return to baseline physiological balance after the stress ends.
Gastric mucosa vulnerability
Stress-related decrease in protective mucus and regeneration, increasing ulcer risk.
Coping by sleep and diet
Strategies to manage stress by rest and nutrition.
Timeline of stress effects
Acute stress may enhance function; prolonged stress can cause damage and disease.
Positive coping outcomes
Using effective coping strategies to restore homeostasis and health.
Negative coping outcomes
Maladaptive strategies that worsen stress and health.
Stress as a precipitating factor
Stress can trigger or worsen diseases (asthma, ulcers, infections, etc.).
Adaptive vs maladaptive responses
Adaptive responses help cope; maladaptive responses hinder recovery.