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What is homeostasis?
The regulation of the internal conditions in a cell or organism to maintain optimum conditions for function in response to internal and external changes
What key three factors does homeostasis in human control?
Blood glucose concentration, body temperature, water levels
What does the nervous system do in humans?
Enable humans to react to their surroundings and to coordinate their behaviour
What is the Central Nervous System?
The brain and spinal cord
What does the Central Nervous System do?
Coordinates the response of effectors which may be muscles or gland secreting hormones
What is the Central Nervous System sequence?
Stimulus --> Receptor --> Coordinator --> Effector --> Response
What is the endocrine system?
A system composed of glands which secret chemicals called hormones directly into the bloodstream
What is the pituitary gland?
The 'master gland' in the brain which secretes hormones into the blood in response to body conditions
What does the pancreas do?
Monitor and control blood glucose concentration
What happens when the blood glucose concentration is too high?
The pancreas produces the hormone insulin that causes glucose to move from the blood into the cells
H What happens when the blood glucose concentration is too low?
The pancreas produces the hormone glucagon that causes glycogen to be converted into glucose and release into the blood
What is glucose converted to in liver and muscle cells?
Glycogen
What is Type 1 diabetes?
A disorder where the pancreas fails to produce sufficient insulin
What is Type 2 diabetes?
Where body cells no longer respond to insulin produced by the pancreas
How do you treat Type 1 diabetes?
Through insulin injections
How do you treat Type 2 diabetes?
Through a carbohydrate-controlled diet and exercise regime
What is oestrogen?
The main female reproductive hormone produced in the ovary
What is ovulation?
Where a mature egg is released
What is testosterone?
The main male reproductive hormone produced by the testes and it stimulates sperm production
Name the hormones involved in the menstrual cycle
Follicle stimulating hormone (FSH), Luteinising hormone (LH), Oestrogen, Progesterone
What does Follicle stimulating hormone (FSH) cause?
The maturation of an egg in the ovaries
What does Luteinising hormone (LH) do
Stimulates the release of the egg
What is the role of Oestrogen and Progesterone?
They are involved in maintaining the uterus lining
What do oral contraceptives do?
Contain hormones to inhibit FSH production so that no eggs mature
How do injection, implant or skin patch contraceptives work?
By slowly releasing progesterone to inhibit the maturation and release of eggs for a number of months or years
Name two barrier methods of contraception
Condom, diaphragms
What is an intrauterine device?
A device that prevents the implantation of an embryo or releases a hormone
What do spermicidal agents do?
Kill or disable sperm
HT What are the four steps of In Vitro Fertilisation (IVF) treatment?
A mother is given FSH and LH to stimulate maturation of several eggs, eggs are collected from the mother and fertilised by sperm from the father in the laboratory, the fertilised eggs develop into embryos. One or two embryos are inserted into the mother's uterus
HT Give three negative about IVF
Emotionally and physically stressful, success rates are not high, can lead to multiple births which are a risk to both babies and the mother
HT What is adrenaline?
A hormone produced by the adrenal gland in times of fear or stress
HT What are the effects of adrenaline?
Increases heart rate, boosts the delivery of oxygen and glucose to the brain and muscles
HT What is thyroxine?
A hormone produced by the thyroid gland that stimulates basal metabolic rate
HT How are thyroxine levels controlled?
By negative feedback
What process leads to the formation of non-identical cells?
Meiosis
What process leads to the formation of identical cells?
Mitosis
What are the male gametes in animals?
Sperm cells
What are the female gametes in animals?
Egg cells
What are the male gametes in plants?
Pollen cells
What are the female gametes in plants?
Eggs cells
Which reproduction process involves the mixing of genetic material?
Sexual reproduction
Which reproduction process involves no mixing of genetic material?
Asexual reproduction
What is formed when cells in reproductive organs divide by meiosis?
Gametes
What happens to the number of chromosomes in gametes during meiosis?
It halves
What happens to gametes during fertilisation?
They join to restore the normal number of chromosomes
After fertilisation how does the new cell divide?
By mitosis
What is the basic structure of DNA?
A polymer made up of two strands forming a double helix
What is a gene?
A small section of DNA on a chromosome that controls a characteristic of that organism
What is a genome?
The entire genetic material of an organism
What is a chromosome?
A structure that contains the DNA of an organism
What is an allele?
The different form of a single gene
What is a phenotype?
The alleles present in an organism
What do we mean by a dominant allele?
A characteristic that is always expressed
What is a recessive allele?
A characteristic that is only expressed if two copies of the allele are present
What are homozygous alleles?
Where in an organism, two alleles are the same
What are heterozygous alleles?
Where in an organism, two alleles are different
What is polydactyly?
Having extra fingers or toes
Is polydactyly a dominant or recessive allele?
Dominant
What is cystic fibrosis?
A disorder of cell membranes
Is cystic fibrosis a dominant or recessive allele?
Recessive
How many pairs of chromosomes are there in the human body?
23
What sex is XX?
Female
What sex is XY?
Male
What is variation?
Differences in the characteristics of individuals in a population
What causes variation?
Differences in the genes inherited, the conditions in which they have developed or a combination of both
Describe the genetic variation within a population of a species
Usually extensive
How does variation occur?
Through mutations
How often do mutations occur?
Continuously
What is evolution?
A change in inherited characteristics of a population over time through a process of natural selection which may result in the formation of a new species
What is the theory of evolution by natural selection?
That all species of living things have evolved from simple life forms that first developed more than three billion years ago
When does one species form into two new species?
When the one species becomes so different in phenotype that they can no longer interbreed to produce fertile offspring
What is selective breeding?
The process by which humans breed plants and animals for particular genetic characteristics
What is a danger of selective breeding?
'Inbreeding' where some breeds are particularly prone to disease or inherited defects
List four desired characteristics from selective breeding
Disease resistance in food crops, animals that produce more meat or milk, domestic dogs with a gentle nature, large or unusual flowers
What is genetic engineering?
A process which involves modifying the genome of an organism by introducing a gene from another organism to give a desire characteristic
What are genetically modified crops?
Crops that have had their genes modified by genetic engineering
What are typical characteristics of genetically modified crops?
Resistance to insect attack, resistance to herbicides, increased yields
What is the evidence for evolution?
Fossils and antibiotic resistance in bacteria
What are fossils?
The 'remains' of organisms from millions of years ago, which are found in rocks
How are fossils formed?
From parts of organism that have not decayed, where parts of an organism are replaced by minerals as they decay or as preserved traces of organisms, such as footprints, burrows and rootlet traces
What is extinction?
When there are no remaining individuals of a species still alive
What factors contribute to the extinction of a species?
Environment changes, new predators, a new disease, they cannot compete with another species for food, a catastrophic event (like a volcanic eruption)
Why can bacteria evolve quickly?
Because they reproduce at a fast rate
What is MRSA?
A relatively common 'superbug' that is really hard to get rid of
Who developed the system of classification of living things?
Carl Linnaeus
Name the seven parts of the classification system
Kingdom, phylum, class, order, family, genus and species
How are organisms names?
By the binomial system of genus and species
Who developed the 'three-domain system' of classification?
Carl Woese
Name the three domains developed by Carl Woese
Archaea, Bacteria and Eukaryota
What are Archaea?
Primitive bacteria usually living in extreme environments
What are four examples of Eukaryota?
Protists, fungi, plants and animals
Define ecosystem
The interaction of a community of living organisms (biotic) with the non-living (abiotic) parts of their environment
What do plants in a community compete with each other for?
Light, space, water, mineral ions
What do animals in a community compete with each other for?
Food, mates, territory
What is interdependence?
Where in a community each species depends on other species such that if one species is removes it affects the whole community
What is a stable community?
One where all the species and environmental factors are in balance so that the population sizes remain fairly constant
List eight abiotic factors
Light intensity, temperature, moisture levels, soil pH, mineral content, wind intensity and direction, carbon dioxide levels (for plants), oxygen levels (for aquatic animals)
List four biotic factors
Availability of food, new predators arriving, new pathogens, one species outcompeting another so that numbers are no longer sufficient to breed
What are adaptations?
Features that organisms have that enable them to survive in the conditions in which they normally live
Name the three types of adaptation
Structural, behavioural, functional