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RA causes
Unknown
Suspected: Infection, Genetic, and Smoking
OA - causes
Idiopathic
or secondary to injury or inflammatory pathway
RA- Signs and Symptoms
WAXES and WANES
morning stiffness that lasts more than 1 hour before able to move
Maliase
usually symmetrical, starting with smaller joint of hands, feet, wrists and then moving to bigger joints
OA - Signs and Symptoms
asymmetric joint pain, insidiously: slow without s/s at 1st
follows physical activity, morning stiffness last less than 1 hour, WORSE at the end of the day, crepitus (bone on bone), cool joints, limited ROM, nodes
MC in fingers, thumbs, neck, knees, hips, lower back
RA - Differentials
Lupus, psoriatic arthritis, fibromyalgia
OA - Differentials
joint injury, RA, gout
RA - Diagnostics
CBC, ESR, WBC, CMP, Rheumatoid Factor
Synovial Fluid - cloudy and WBC
Anti-CCP
OA - Diagnostics
GOLD - xray - used to r/o other arthritis
shows the osteophytes and joint narrowing
**usually diagnose based off S/S
NEGATIVE: sed rate, rheumatoid factor, ANA
RA - Pharm Dose
1st line - NSAIDS or DMARDS (Celebrex)
400 mg day one, then 200mg daily after (maybe add PPI)
methotrexate
7.5mg PO once a week
RA - Pharm SE
1st line
Celebrex
SE: increased risk for MI/Stroke, and fatal GI events
methotrexate
SE: elevated LFTs, nausea, infection, anemia, abdominal discomfort
!!!Can cause hepatotoxicity, monitor CBC, liver profile THIS IS ESSENTIAL !!!!!
OA - Pharm and SE
conservative tx first- exercise and heat
THEN:
-NSAIDS, SE: gastric ulceration, renal impairment, fluid retention ** give PPI if long-term
-steroid injection, SE: wt gain, increased appetite, mood changes
RA - nonpharm
rest with flare-ups
exercise when no flare-ups
- joint replacement if extensive damage
OA - nonpharm
prevent further cartilage destruction - prevention is best (maintain wt, prevent injury)
Supervised activty
rest, braces, heat/cold, local creams
surgery
RA - pt edu
Diagnosis and Prognosis
Med SE
Balance between rest and exercise
OA - pt edu
muscle strengthening
diagnosis and prognosis
med SE
*Set reasonable goals, as being pain free is not likely due to the progressive nature of the disease but the goal is to make activities of daily living and least amount of pain
RA - referral
Refer to rheumatologist ASAP
OA - referral
PT and supervised exercise
surgery or RA
RA - F/U
3-4 months during tx
OA - F/U
regular eval for pain and med management
if on NSAIDS: CBC, renal and occult stool (be off NSAIDS for 3 days before this test)
taper corticosteroids
taper dosage by 50% of physiological values over 7 days, switch from multi doses to one dose
*mx for s/s of insufficiency: muscle weakness, lethargy, hypoglycemia
Cox 1 - Tissue Sites
all tissues
protecting gastric mucosa,
supporting renal function
promoting platelet aggregation
Common COX 1 and COX2 medication
Tylenol, NSAIDS
Cox 1 - Benefits
works as protection to MI/stroke
Cox 1 - Bad effects
gastric ulceration
renal impairment
bleeding
Cox 2 - Tissue sites
injured tissue site
-mediates inflammation
-sensitizes receptors to painful stimuli.
in the brain: where it mediates fever and contributes to perception of pain
in kidneys: where it supports renal function
blood vessels: where it promotes vasodilation
in the colon where it can contribute to colon cancer
COX 2 ONLY - Common Medications
celebrex
Cox 2 - Benefits
suppresses inflammation
protective against colorectal cancer
alleviates pain
Cox 2 - Bad Effects
bleeding
gastric ulceration
renal impairment
increased risk of MI/stroke
Who Gives NP prescriptive authority?
Texas State Board of Nursing
What do you need for Prescriptive Authority?
DEA #
obtain certification from State Board of Nursing
collaborative agreement with an doctor
*can only Rx C111-CV
Can only prescribe in an ER in Hospital, pt in hospital after 24 hours, and in terminally ill pt or hospice situation
Gout - Causes/RF
Renal impairment
Purine High Diet
cirrhosis
HTN
Obesity
Polynesian Race
Gout - Diagnostics
Synovial fluid aspiration- presence of MUC (monosodium urate crystals) crystals in joint fluid or tophus
Gout - Nonpharm
rest
dietary changes (decrease purine intake)
maintain healthy wt
increase water intake 3L/day
Gout - Pharm 1st line Acute
less than 3 flare-ups a year
- NSAIDS: Naproxen 500mg BID
Glucocorticosteroids (in contra to NSAIDS)
- prednisone 30mg daily x 5 days
Gout - Pharm 1st line Preventative
Allopurinol - 100mg once initially then 100mg weekly to maintain serum urate levels
max 800 mg/day
EDU: initial treatment may illicit gout attack
Gout- Pt EDU
Avoid Purine Rich Foods
and Alcohol
Gout - Referral
disease progressing despite uric lowering treatment
unclear gout diagnosis
if tx is effective but drug toxicity occurs from drugs
attack has not responded to tx
Gout - F/U
mx for recurrent attacks and tophi development
*uric lowering tx - every 1-3 months then every 6- 12 months
*NSAIDs, colchicine, and allopurinol,
complete blood count, renal function tests, and liver function tests should be obtained every 3 to 6 months.
Rotator Cuff Injury - Body parts Involved
supraspinatus
infraspinatu
teres minor
subscapularis.
Rotator Cuff Injury - Diagnostics
Supraspinatus test
Drop-arm test
Neer Impingement test
Hawkins-Kennedy impingement test,
Apprehension test
MRI after PE exam tests to locate extent of injury
Supraspinatus test
identifies tear and/or impingement of supraspinatus tendon or possible suprascapular nerve neuropathy
Drop Arm Test
Positive result if: Severe pain or inability of the patient to return the arm to the side slowly
A positive result indicates a rotator cuff tear.
Rotator Cuff Injury - s/s
pain and weakness - will not be able to hold arm straight up
loss of ROM
inclination to keep shoulder inactive
Rotator Cuff Injury - nonpharm
Rest
Ice/heat therapy
work activity modifications
PT for strengthening and stretching exercises
Rotator Cuff Injury - pt EDU
NSAID use or steroid injection
Rest shoulders
complications if left untreated: loss of shoulder function
Rotator Cuff Injury - F/U and Referral
2-4 weeks for evaluation
if not responding to treatment within 3-6 weeks
if rotator cuff tear - need surgery in 2 weeks
Low Back Pain - MC cause top 3
70% lumbar strain
4% herniated disc
4% Osteoporotic Fracture
Low Back Pain - Differentials
Low back strain, Osteoarthritis, Osteomyelitis
Kidney disease, ovarian cancer/cysts, appendicitis
Low Back Pain - Diagnostics for top 3
Herniated Discs- Straight Leg test or Crossed Leg Test, Xray and MRI, Toe and Heel walk
pulses for abdominal aneurysm
squat test, point-point discrimination, Reflexes
Low Back Pain - Pharm
1st line: NSAIDS, Tylenol, muscle relaxants, and opioids
NSAIDS - long-term use PPIs and mx CBC, liver fx, renal fx,
Muscle relaxants - Flexeril 5mg TID
SE: drowsiness and physical dependence
2nd line: steroid injections
3rd line: conservative therapy, surgical
Low Back Pain - nonpharm
restrict activities that would aggravate condition
heat and cold therapy
spinal manipulations
90% resolves within 4-6 weeks
Low Back Pain - RED FLAGS
younger than 20, older than 50
hx of IV drug use
hx of chronic steroid use
hx of cancer
recent bacterial infection
wt loss with back pain
nocturnal or unrelenting back pain that is worse in supine position
hx of immunosuppression
hx of recent trauma or TB
Low Back Pain - F/U
severe pain 24-72 hours
moderate pain 7-10 days, then every 2-4 weeks until pain is resolved
Sprain and Strain- Mj Differences
Sprain: tendon and muscle involvement
Strain: ligament involvement
Sprain and Strain - Diagnostics
PE first: location of pain, description of pain, neurovascular exam
Ask: How injury occurred, sport or movement that caused injury
Anterior/Posterior Drawer Test
Talar Tilt test
External Rotation Test
Squeeze Hopkins Test
Ottawa Rules for Imaging. Xray if fracture suspected, MRI if sprain/strain is severe
Sprain Grades
1) some stretching and micro tears in ligament
2) large but incomplete tear
3) complete tear of the ligament
Strain Differentials
sprain, fracture, tendonitis
Sprain and Strain - nonpharm Grades 1, 2, 3
GRADES 1-2
Protection (brace, splint, crutches)
Rest
Ice (every 20 min every 2 hours)
Compression
Elevation
Rehabilitation (PT ROM)
- muscle conditioning
-functional exercises
- electrotherapeutic modalities
Grade 3 - refer
Sprain and Strain - Pharm and SE
NSAIDS
SE: renal impairment, hepatic impairment, gastric ulceration, bleeding
Tylenol
SE: blistered skin, hoarseness, difficulty breathing/swallowing
Opioids
SE: constipation, dependency, respiratory depression
Sprain and Strain: EDU
when and how to take pain medication
difference between sprain and strain
PRICE treatment
ROM exercises
Sprain and Strain - Referral
eversion or Grade 3, no improvement in a week - orthopedist
after 48 hours refer to PT for ROM
Sprain and Strain - F/U
2 weeks to evaluate pain and swelling
after 48 hours refer to PT for ROM
Ankle Fracture - Assessment
PE: point of tenderness, swelling, symmetry, poor ROM, effusions or crepitus
Ankle Fracture - RF
osteoporosis, smoking, malignancies, menopause, sedatives in elderly, falls
Ankle Fracture - Differential
sprain, strain, contusion, dislocation
Ankle Fracture - Diagnostics
PE: neuro exam to r/o nerve and BV involvement
Xray and MRI
Ankle Fracture - nonpharm SPICE
Splint
Protect
Ice
Compression
Elevation
Ankle Fracture - referral
Casting/Traction - Orthopedist
Ankle Fracture - Pt EDU
signs of infection
wound management if applicable
edema and pain control methods
appropriate activity and rest
Medication SE and Use
Ankle Fracture - F/U
depends on severity 6-8 weeks for repeat xray
ACL or PCL tear - Define
anterior cruciate ligament (ACL)
Posterior cruciate ligament (PCL)
ACL or PCL tear - Causes
twisting and hyperextension
ACL or PCL tear - Differentials
meniscus tear, PCL sprain or strain, MCL sprain
ACL or PCL tear - s/s
ACL tear has 4 classic symptoms:
-Hear a pop from inside the knee
-Feel the knee give away at the time of the injury
-Swollen immediately, or within a few hours
-Severe pain - can not continue to play
ACL tear - Diagnostics and Positives
Lachmans Test
*positive test indicated by noticing abnormal anterior displacement of tibia forward
Meniscus Tear - Diagnostics
McMurray test-
*Positive test: hearing a crepitus associated with pain.
Thessaly's test-
*Positive test: locking movement or "pop"
sensation with pain in knee.
PCL tear - Diagnostics and Positives
Posterior drawer test -
Posterior sag test-
*Positive test is indicated when the posterior displacement of the tibial tuberosity is more in the affected limb
Herniated Disc - Diagnostics
Straight Leg Test
Phalen Test - What is it?
Hold hand inverted for 60 seconds
Positive signs = pain, numbness, tinging.
VERY SPECIFIC TO CARPAL TUNNEL
ACL or PCL tear - nonpharm
RICE or PRICE
ACL or PCL tear - pharm and DI
NSAIDS, Opioids, tylenol
ACL or PCL tear - pt EDU
avoid aggravating movements
safe use of crutches, braces
PRICE
ACL or PCL tear - Referral
ALWAYS for a complete tear to orthopedist/surgery
ACL or PCL tear - F/U
1 week with ortho
Hurt Knee - Diagnostics
MRI for extent of injury
Hurt Knee - Differentials
fracture, joint or ligament injury
Hurt Knee - nonpharm
conservative treatment - PRICE
exercise and physiotherapy needed to decrease adhesions
surgery
Hurt Knee - Referral
if grade 3 sprain
acl complete tear
fracture
Hurt Knee - F/U
ACL tear- 1 week
Sprain/Strain - 2 weeks to evaluate for pain, swelling, weight bearing status