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Neuroscience
transduction
mehcanoreceptors
photoreceptors
chemoreceptors
thermoreceptors
proprioceptors
rods
cones
olfactory receptors
corpuscles
muscle spindles
golgi tendon organ
intensity
type
timing
location
frequency modulation
recruitment
adaptation
slow adapting
rapid adapting
receptive field
spatial attributes
resolution
receptive field size
fine descrimination
receptor density
cortical representation
topography
mechanoreceptor types
meissner's corpuscle
pacinian corpuscle
merkel's disk
ruffini endings
divergently
convergently
feedforward inhibition
lateral/surround inhibition
feedback inhibition
descending inhibition
perceptual/inattentional blindness
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light
Modality: vision
Stimulus: ___
Receptor class: photoreceptors
Receptor cells: rods and cones
sound/pressure waves
Modality: audition/hearing
Stimulus: ___
Receptor class: mechanoreceptors
Receptor cells: hair cells on cochlea
gravity, acceleration, head motion
Modality: vestibular/balance
Stimulus: ___
Receptor class: mechanoreceptors
Receptor cells: hair cells in vestibular labyrinths
chemicals (T)
Modality: gustatory/taste
Stimulus: ___
Receptor class: chemoreceptors
Receptor cells: taste buds
chemicals (O)
Modality: olfactory/smell
Stimulus: ___
Receptor class: chemoreceptors
Receptor cells: olfactory sensory neurons
skin deformation and motion
Modality: Touch
Stimulus: ___
Receptor class: mechanoreceptors
Receptor cells: Merkel’s discs
muscle length and force, joint angle
Modality: proprioception
Stimulus: ___
Receptor class: proprioceptors and mechanoreceptors
Receptor cells: muscle spindle, golgi tendon organ, joint capsules
noxious stimuli (thermal, mechanical, chemical)
Modality: pain
Stimulus: ___
Receptor class: chemoreceptors
Receptor cells: free nerve endings in all tissues but CNS
transduction
conversion of stimulus energy into electrical energy as action potential
function of ALL receptors
transmits information about stimulus’
type
intensity
timing
location
olfactory chemoreceptors
cilia on mucosal surface bind specific odorant molecules and depolarize sensory nerve through a second messenger system.
firing rate signals the concentration of odorant molecules
rods and cones
outer segments contain light-sensitive rhodopsin which change conformation when absorbing light of particular wavelengths.
stimulation reduces cGMP concentration in cytoplasm, closing cation channels and hyperpolarizing the cell
how much of each population of receptors is firing is what determine perception
corpuscles
rapidly adapting mechanoreceptors in the skin that react to pressure as they are fluid filled capsules. When the skin stretches, the stretch-sensitive channels open and depolarize the free nerve ending.
muscle spindle
sits parallel to the muscle
deformed when the muscle is stretched, thus responds to changes in muscle length
also a type of proprioceptor
golgi tendon organ
in series with the muscle
deformed when the muscle contracts, thus responds to changes in muscle force
also a type of proprioceptor
lowest, strongest
the best stimuli is the one that activate the receptors at the ___ energy, and evokes the ___ response
intensity
the ___ of a stimulus is based on frequency modulation and recruitment
frequency modulation
afferent fibers discharge more often as the stimulus intensity increases
recruitment
the stimulus reaches threshold/activates more receptors and thus recruit more afferent fibers to discharge
allow different sensitivity ranges from different afferent fibers avoiding restricting the range of stimuli the body can respond to
adaptation
the slowing of action potential frequency with unchanging stimulus
translate to perception as a constant stimulus fades from consciousness
slowly adapting
___ receptors = signal duration
background firing
rate of firing is proportional to intensity of stimulus
fires the whole time the stimulus is applied
rapidly adapting
___ receptors = signal change in stimulus
stops firing when stimulus becomes constant
corpuscles fall into that category as they fire when the fluids compress the central nerve part when stimulus applied, and after it reforms under stimulus, it is deformed again when stimulus taken away.
receptive field
area of sensory surface which, when stimulated with an appropriate stimulus, activates or inhibits sensory neurons
area of receptive surface or stimuli space that changes the activity of a neuron
can be excitatory or inhibitory
conveys spatial attributes of visual, tactile, auditory stimuli: location, orientation, dimensions, shape, tonal frequency
resolution
__ is proportional to the total number of receptors and inversely correlated with the area of the receptive field
smaller
___ receptive fields = higher spatial discrimination = better resolution
higher, smaller, greater
high resolution and fine discrimination are coded by:
__ density of peripheral receptors
__ receptive fields
___ cortical representation
topography
orderly representation of inputs
for human cortex, more space dedicated to fingertips, lips, tongue, and face as those are the main tools humans use to explore the world
for mouse cortex, more space dedicated to whiskers and paws
Meissner’s corpuscle
superficial/close to skin surface
rapidly adapting
responds to stroking/fluttering sensation
mechanoreceptor
Merkel’s discs
superficial/close to skin surface
slowly adapting
responds to pressure and texture stimuli
mechanoreceptor
ex: good for reading brail
Pacinian corpuscle
deep into the skin/larger
rapidly adapting
responds to vibrations
mechanoreceptor
Ruffini endings
deep into the skin/larger
slowly adapting
responds to skin stretch
mechanoreceptor
integration
___ of information happens at each neural center
divergently
each neuron passes information ___ aka to more than one neuron
convergently
each neuron receives information ___ aka from more than one neuron
the reason why receptive field of relay neurons are ALWAYS LARGER than sensory neurons’.
convergent connections
___ allow higher order (cortical) neurons to abstract complex information from simple patterns
higher order neurons more concerned with the behavioral importance of stimuli
feedforward inhibition
AKA lateral/surround inhibition
afferent fibers terminate on inhibitory interneurons as well as next excitatory neuron
enhance contrast between strongly and weakly excited cells
restrict excitation to center zone where the stimulation is the strongest
feedback inhibition
collateral axons of neurons in output pathway terminate on inhibitory interneurons
control local spread of activity/local excitability
descending inhibition
allows cortical neurons to control the relay of sensory information centrally
mechanism of selecting specific input for attention
modulates strength of sensory inputs
___ feedback is specific and goes both ways between cortex and thalamus
morphology
___ of receptors varies with the type of stimulus that best activates them
fingertips, back
resolution of spatial coding varies across the body: higher resolution in the ___ and lower resolution in the ___