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Selective toxicity toward microorganisms
Antimicrobial drugs are effective because they exhibit:
Patient's favorite color
Which of the following is NOT a factor in selecting an antimicrobial agent?
Empiric therapy
Immediate administration of antibiotics before bacterial identification is called:
Gram stain
Which laboratory test is commonly used for the rapid identification of bacteria?
Which antibiotic the microorganism is sensitive to
Antimicrobial susceptibility tests are performed to determine:
All of the above
Which patient factor should be considered before prescribing antibiotics?
Once-daily high-dose administration
Which dosing strategy is most appropriate for antibiotics that exhibit concentration-dependent killing?
Lowest concentration that inhibits bacterial growth
The Minimum Inhibitory Concentration (MIC) is the:
Post-antibiotic effect (PAE)
Drugs that continue to suppress bacterial growth after antibiotic levels fall below the MIC exhibit:
Isoniazid
Which antibiotic is classified as a narrow-spectrum antimicrobial?
Extended-spectrum antibiotic
Ampicillin is considered an:
Tetracycline
Which antibiotic is considered broad-spectrum?
Superinfection
Overuse of broad-spectrum antibiotics may result in:
Ribosomes
Protein synthesis inhibitors act primarily by targeting bacterial:
30S ribosomal subunit
Tetracyclines inhibit protein synthesis by binding to the:
Tooth discoloration
Which adverse effect is commonly associated with tetracyclines?
Pregnant women and children under 8 years old
Tetracyclines are contraindicated in:
Ototoxicity
Aminoglycosides commonly cause:
Hearing loss
Which adverse effect of aminoglycosides may become irreversible?
50S ribosomal subunit
Macrolides inhibit bacterial protein synthesis by binding to the:
Chloramphenicol
Which antibiotic is associated with Gray Baby Syndrome?
Erythromycin
Clindamycin has the same mechanism of action as:
Inhibiting bacterial cell wall synthesis
Penicillins kill bacteria primarily by:
Hypersensitivity reactions
Which adverse effect is commonly associated with penicillin therapy?
Penicillins
Cephalosporins have the same mechanism of action as:
DNA gyrase and topoisomerase IV
Fluoroquinolones inhibit bacterial:
Tendon rupture
Which adverse effect is characteristic of fluoroquinolones?
Dihydropteroate synthetase
Sulfonamides inhibit bacterial:
Dihydrofolate reductase
Trimethoprim inhibits bacterial:
Cotrimoxazole
Which combination antibiotic contains sulfamethoxazole and trimethoprim?