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Twitch
single contraction of one muscle fiber produced by single stimulus
7-100ms
Twitch sequence
stimulus
contraction
relaxation
Muscle fiber types
Fast glycolytic
Fast oxidative-glycolytic
Slow oxidative
Fast glycolytic
Fastest twitch
fastest myosin
glycolysis for ATP
quick bursts
fatigues quickly
Fast oxidative glycolytic
Both aerobic respiration and glycolysis
fast myosin
fatigues less quickly
Slow oxidative
Aerobic respiration
slow myosin
low fatigue
Twitch 3 phases
Latent
contraction
relaxation
Latent period
Between stimulus and contraction
AP propagates
Ca released
Contraction
Cross bridge cycle
Relaxation
Ca pumped back into SR
Cross bridge detach
Treppe
next stimulus comes at end of previous
increase max tension to over 30-50 stimuli
Wave summation
next stimulus comes before previous relaxation is over
Incomplete tetanus
sustained high frequency of stimulation
wave summation
reaches plateau
quick periods of partial relaxation
Complete tetanus
Very high frequency of stimulation
no relaxation
rapid APs
sustained high Ca in sarcoplasm
Muscle contraction
tension generated by muscle
= the sum of tensions generated by its fibers
Variation in tension of muscle
frequency of stimulation
number of fiber contractions at once
Motor units
1 motor neuron and all the fibers it controls
small MU
4-6 fibers
Ex) eye muscle
large MU
1000-2000 fibers
Ex) rectus femoris
MU intermingled
distribute force on tendon
Isometric
muscle generates tension
does NOT shorten
Isotonic
muscle generates tension
muscle changes length
Concentric
shortens
Eccentric
lengthens
Functions of the nervous system
Sensory
integration
motor
Sensory
recognize changes in environment
Integration
analysis of sensory info
info storage
decisions
Motor
signals to effectors (muscles or glands)
Organization of the Nervous system
Central
Peripheral
cranial nerves
Sensory division
input into CNS
somatic
special
Somatic senses
touch
nociception
proprioception
special senses
sight
hearing
taste
smell
motor division of PNS
motor output from CNS
somatic- voluntary
autonomic- involuntary
Autonomic
Sympathetic- fight or flight
Parasympathetic- rest and digest
smooth and cardiac muscle and glands
Enteric
controls digestive system
smooth muscle and glands of GI tract
Nerves
bundles of axons
from multiple neurons
Nerves made of
axons
schwann cells
CT
blood vessels
no neurosomas
Neurosomes in:
ganglia
spinal cord
brain
Nerves inside brain?
no
Cell bdy
neurosoma;soma