Red blood cell morph causes

What causes microcytes?

Iron deficiency anemia, thalassemia minor, chronic inflammation, lead poisoning, hemoglobinopathies, and sideroblastic anemia

What causes macrocytes?

Liver disease, Vitamin B12 deficiency, folate deficiency, neonates and reticulocytotic

What causes heterogenous erythrocytes?

Anemias

What causes two distinct RBC population?

Transfusions, myelodysplastic syndromes, sideroblastic anemia

What causes hypochromia?

iron deficiency anemia, thalassemia, sideroblastic anemia, lead poisoning

What causes dichromic populations of RBCs?

Transfusions and sideroblastic anemia

What causes polychromasia?

Acute and chronic hemorrhage, hemolysis, neonates

What causes acanthocytes?

Sever liver disease, splenectomy, malabsorption, hypothyroidism, vitamin E deficiency, and abetalipoproteinemia

What causes schistocytes?

Microangiopathic hemolytic anemia, severe burn and renal graft rejections

What causes burr cells?

uremia, pyruvate kinase deficiency, microangiopathic hemolytic anemia, neonates, excess EDTA, and slow drying of blood film artifact

What causes spherocytes?

Hereditary spherocytosis, some hemolytic anemia, transfused cells and severe burns

What causes codocytes?

Hemoglobinopathies, thalassemia, iron deficiency anemia, splenectomy, and obstructive liver disease

What cause drepanocytes?

Homozygous hemoglobin S disease, sometime hemoglobin SC disease

What causes hemoglobin CC crystals?

Homozygous hemoglobin C disease

What causes hemoglobin SC crystals?

Hemoglobin SC disease

What cause elliptocytes/ovalocytes?

Hereditary elliptocytosis or ovalocytosis, thalassemia major, iron deficiency anemia, megaloblastic anemias, and myelophthisic anemias

What causes dacryoctes?

Primary myelofibrosis, thalassemia, myelophthisic anemia and other causes of extramedullary hematopoiesis

What causes stomatocytes?

Hereditary stomatocytosis, alcoholism, liver disease, Rh null phenotype and artifact

What causes rouleaux?

Acute and chronic inflammatory disorders, plasma cell myeloma and lymphoplasmacytic lymphoma

What cause autoagglutination?

antigen-antibody reactions

What causes howell-jolly bodies?

splenectomy, hypersplenism, megaloblastic anemia, hemolytic anemia

What are howell-jolly bodies composed of?

DNA

What causes basophilic stippling?

Lead intoxication, thalassemia, abnormal heme synthesis

What is the composition of basophilic stippling?

RNA

What causes pappenheimer bodies?

Splenectomy, hemolytic anemia, sideroblastic anemia, hemoglobinopathies

What are pappenheimer bodies composed of?

Iron

What causes cabot rings?

Myelodysplastic syndrome, megaloblastic anemia

What are cabot rings thought to be composed of?

The mitotic spindle

What causes heinz bodies?

Unstable hemoglobin, hemoglobinopathies, erythrocyte enzyme deficiencies

What are heinz bodies made of?

Denatured hemoglobin