QC1 Pre Exam

Validation

The primary goal in pharmaceutical manufacturing is to confirm that a process consistently produces a product meeting its specifications.

Variable Defect

Defect based on the ability to measure the defect directly

Titration helps to determine the active ingredient concentration in pharmaceuticals.

True

Measure the purity of the substance.

Primary aim of assay in Pharmaceutical Analysis

A secondary standard must be pure, stable, and have a known composition to provide accurate results.

False

Minor defect in final inspection of a pharmaceutical product? Best action is:

Document the defect and continue with the release of the product.

The primary goal of volumetric analysis

To measure the volume of a solution with a known concentration

The primary focus of specifications in the context of pharmaceutical products

Defining the market demand for the product.

Quality Assurance

This describe the total arrangement made to ensure that pharmaceutical products are of the required quality

Primary standards are chosen for their stability and high purity, making them ideal for accurate standardization.

Strongly Disagree

The relationship between accuracy and precision

Both accuracy and precision are necessary for reliable results.

The normality equation M1V1 = M2V2 relates the volumes and normalities of the acid and base in a titration.

False

Titrant

The reagent with known concentration

Hygroscopic Nature

NOT a characteristic of a primary standard

Blank titration measures the potential difference to determine the endpoint.

False

The purpose of a blank titration

To remove errors by accounting for non-analyte factors

Endpoint in titration is detected by a physical change, such as a color change.

True

Secondary Titration

The type of titration when the reaction between the analyte and titant proceeds slowly

Residual titration is used when the analyte is first reacted with an excess reagent, and the excess is then titrated.

False

End, Equivalence, and Stoichiometric Point

The point at which equal moles of titrant and analyte have reacted

Titration is employed to synthesize new pharmaceutical compounds.

False

Titration is a key analytical technique for qualifying the concentration of active ingredients in pharmaceuticals.

False

If a sharp endpoint is not achieved in a titration, add more titrant rapidly until a change is observed.

False

If a sharp endpoint is not achieved in a titration, stir the solution continuously and add the titrant slowly.

True

If a sharp endpoint is not achieved in a titration, see a different indicator to find the endpoint.

False

If a sharp endpoint is not achieved in a titration, iscard the titration and start over.

False

If a sharp endpoint is not achieved in a titration, increase the concentration of the analyte.

False

Diluting a solution to double its volume halves its normality since concentration is inversely proportional to volume.

True

Buffers are used to increase the reaction rate in titrations.

False

Bromophenol blue is a suitable indicator for strong acid strong base titrations due to its color change in the basic pH range.

False

In some chemical compounds, the number of grams in its concentration as Normality is the same as in its Molarity.

True

Molarity is the number of moles of solute per liter of solution, making it a straightforward measure of concentration.

True

Molarity is the number of moles of solute per liter of solution, making it a straightforward measure of concentration.

True

The color of the indicator does NOT affect the accuracy of a titration.

True

The precision of the burette used does NOT affect the accuracy of a titration.

False

The concentration of the standard solution does NOT affect the accuracy of a titration.

False

The primary standard must be non-hygroscopic, to ensure it dissolves easily in water.

False

The primary standard must be non-hygroscopic, to avoid any changes in color.

False

The primary standard must be non-hygroscopic, to allow for easier titration.

False

The endpoint in titration, is the point where the solution is saturated.

False

The endpoint in titration, is the point at which a physical change indicates chemical equivalence.

True

NaOH

This/these substance/s absorb/s moisture from the air, making it challenging to store without altering its concentration.

Secondary standard is used to standardize solutions when a primary standard is unavailable.

True

Endpoint in titration is always occurs at pH 7.

False

None

Ethylene Diamine tetraacetic acid is a reagent used in the titration called:

Neutralization

Direct titration often involves what type of reaction, where an acid reacts with a base.