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genetic predisposition
the increased chance of developing a specific trait or condition due to our genetic code
chromosomes in human cells
46 chromosomes in 23 pairs
chromosome composition
genetic material called DNA
DNA
Deoxyribonucleic acid
genes
discrete segments of DNA that control the production of specific proteins that control some human traits
identical twins
monozygotic twins
develop from one fertilised egg called a zygote
share all the same genetic material
chromosome that determines our sex
23rd pair of chromosomes
males = XY
females XX
Turner's Syndrome
Monosomy X
born with only a single X chromosome in the spot usually occupied by the 23rd pair
symptoms of Turner's syndrome
short stature
webbed necks
difference in physical sexual development
Klinefelter's syndrome
have an extra X chromosome resulting in an XXY pattern
symptoms of Klinefelter's syndrome
minimal sexual development
extreme introversion
Down syndrome
extra chromosome on the 21st pair
physical characteristics indicative of Down syndrome
rounded face
shorter fingers and toes
slander eyes set far apart
intellectual disability
neuroatonomy
study of the parts and functions of neurons
Neurons
individual nerve cells
Dendrites
rootlike parts of the cell that stretch out from the cell body.
dendrites grow to make synaptic connections with other neuron's
cell body (soma)
contains the nucleus and other parts of the cell needed to sustain its life
Axon
wirelike structure ending in the terminal buttons that extend from the cell body
myelin sheath
a fatty covering around the axon of some neurone that speed neural impulses
multiple sclerosis
when the myelin sheath deteriorates around neurone, interfering with neural transmission
terminal buttons are also known as
end buttons
terminal branches of axons
synaptic knobs
terminal buttons
the branched end of the axon that contain neurotransmitters
neurotransmitters
chemicals contained in terminal buttons that enable neurone to communicate.
neurotransmitters fit into receptor sites on the dendeits of neurone
synapse
the space between the terminal buttons of one neuron and the dendrites of the next neutron
neural transmission
the sequence when a neutron transmits a message
1. the terminal buttons of neuron a are stimulated and release neurotransmitters into the synapse
2. the neurotransmitters fit into receptor sites on the dendrites of neuron B
3. if enough neurotransmitters are received, the cell membrane of neuron B becomes permeable and positive ions rush into the cell
4. the charge within the cell becomes +40 mV
5. the change in charge spreads down the length of neuron B
6. when the charge reaches the terminal buttons of neuron B, the buttons release their neurotransmitters into the synapse
resting potential
The difference in electric charge between the inside and outside of a neuron's cell membrane
-70 mV
mostly surrounded by positive ions
threshold
the level of stimulation (the amount of neurotransmitters) required to trigger a neural impulse
action potential
the change in electrical potential associated with the passage of an impulse along the membrane of a muscle cell or nerve cell.
all-or-none principle
the neurone either fires completely or not at all
depolarisation
The change from a negative resting potential to a positive action potential
neural firing
electrochemical process
Electricity travels within the cell (from the dendrites to the terminal buttons), and chemicals (neurotransmitters) travel between cells in the synapse
excitatory neurotransmitters
excite the next cell into firing
inhibitory neurotransmitters
inhibit the next cell from firing
Dopamine
motor movement and alertness
Serotonin
mood control
Norepinephrine
alertness and arousal
glutamate
excitatory neurotransmitter involved in memory
GABA
Important inhibitory neurotransmitter
Endorphins
pain control; involved in addictions
Substance P
pain perception
acetylcholine
motor movement
with an excess or deficit of Dopamine
deficit is associated with Parkinson's disease
excess is associated with schizophrenia
with an excess or deficit of Serotonin
deficit is associated with clinical depression
with an excess or deficit of norepinephrine
deficit associated with depression
with an excess or deficit of glutamate
triggers migraines, seizures
with an excess or deficit of GABA
internalises when having seizures and can cause sleep problems
with an excess or deficit of Endorphins
addictions
with an excess or deficit of Substance P
deficit associated with a lack of pain perception
with an excess or deficit of Acetylcholine
deficit is associated with Alzheimer's disease
also involved in Myasthenia Graves
Myasthenia gravis
Acetylcholine is involved
causes muscle weakness
afferent neurons
sensory neurons
take information from the senses to the brain
interneurons
relay neurons
Once information reaches the brain or spinal cord, interneurons (also called association neurons) take the messages and send them elsewhere in the brain or on to efferent neurons.
efferent neurons
motor neurons
take information from the brain to the rest of the body.
Central Nervous system
consists of our brain and spinal cord
all the nerves housed within bone (the skull and vertebrae)
the spinal cord
a bundle of nerves that run through the center of the spine.
It transmits information from the rest of the body to the brain.
Peripheral Nervous system transmission
Sensory neurons are activated, and this message is transmitted up a neuron that runs from the point of sensation to the base of your spine
The message continues up your spinal cord on more interneurons until it enters your brain through the brainstem
efferent neutrons send corresponding response to effectors
reflex arc pathway
stimulus -> receptor ->sensory neuron -> relay neuron -> motor neuron -> effector -> response.
knee jerk reflex
stimulating the correct area just below your kneecap, causes the leg to jerk without conscious control.
Peripheral nervous system
consists of all the nerves in your body that are not part of the central nervous system
all the nerves not encased in bones
What is the PNS divided into?
Somatic nervous system and autonomic nervous system
somatic nervous system
controls our voluntary muscle movements.
The motor cortex of the brain sends impulses to the somatic nervous system, which controls the muscles that allow us to move
Autonomic nervous system
controls the automatic functions of our body
what is the autonomic nervous system divided into
the sympathetic and parasympathetic nervous systems
sympathetic nervous system
mobilizes our body to respond to stress
accelerates heart rate, blood pressure, and respiration
conserves resources needed for a quick response by slowing down other functions
parasympathetic nervous system
It carries messages to the stress response system that cause many of our body activities to slow down and return the body to homeostasis (its typical level) after a stress response
endocrine gland
a system of glands that secrete hormones that affect many different biological processes in our bodies.
The endocrine system is controlled in the brain by the hypothalamus
adrenaline
Activated during the fight-or-flight response in stressful situations. Speeds up bodily processes.
leptin
Involved in weight regulation. Suppresses hunger (food may be perceived as less appetizing).
Gherkin
Motivates eating/increases hunger (food may be perceived as more appetizing).
Melatonin
Triggers sleep and wakefulness responses in the brain
Oxytocin
Promotes good feelings such as trust and bonding
adrenal glands
produce adrenaline
ovaries and testes
Ovaries and testes produce our sex hormones, estrogen for females and testosterone for males
accidents
psychologists monitor change in behaviour after accidents and record damaged parts of the brain to build associations
Phineas gage
In 1848, a railroad worker named Phineas Gage was involved in an accident that damaged the front part of his brain. Gage became highly emotional and impulsive after the accident. Researchers concluded that the parts of the brain damaged in the accident are somehow involved in emotional control
Lesions
the removal or destruction of part of the brain.
Any time brain tissue is removed (lesioning), researchers can examine behavior changes and try to infer the function of that part of the brain.
frontal lobotomy
used to control mentally ill patients who had no other treatment options
makes patients calm and relieve some serious symptoms
Electroencephalogram
detects brain
Researchers can examine what type of waves the brain produces during different stages of consciousness and use this information to generalize about brain function
used in sleep research to identify the different stages of sleep and dreaming.
Computerized Axial Tomography
uses several X ray cameras that rotate around the brain and combine all the pictures into a detailed three-dimensional picture of the brain's structure
Magnetic Resonance Imaging
uses magnetic fields to measure the density and location of brain material
the patient is not exposed to carcinogenic radiation
Positron Emission Tomography
lets researchers see what areas of the brain are most active during certain tasks
measures how much of a certain chemical (e.g., glucose) parts of the brain are using.
Different types of scans are used for different chemicals such as neurotransmitters, drugs, and oxygen flow.
Functional MRI
combines elements of the MRI and PET scans
show details of brain structure with information about blood flow in the brain, tying brain structure to brain activity during cognitive tasks
Hindbrain
located on top of the spinal cord.
The hindbrain is our life support system
controls the basic biological functions that keep us alive
contains the medulla, pons, and cerebellum
medulla
control of our blood pressure, heart rate, and breathing
located above the spinal cord
pons
located just above the medulla and toward the front
connects the hindbrain with the midbrain and forebrain
also involved in the control of facial expressions.
cerebellum
located on the bottom rear of the brain
coordinates some habitual muscle movements
midbrain
located just above the structures in the hindbrain but still below areas categorized as the forebrain
very small in humans
coordinates simple movements with sensory information
contains reticular formation
reticular formation
a netlike collection of cells throughout the midbrain
controls general body arousal and the ability to focus our attention
if it does not function, we fall into a deep coma
forebrain
The largest and most complicated region of the brain,
including the thalamus, hypothalamus, limbic system, amygdala, hippocampus and cerebrum.
control what we think of as thought and reason
thalamus
located on top of the brain stem
responsible for receiving the sensory signals coming up the spinal cord and sending them to the appropriate areas in the rest of the forebrain
Hypothalamus
small structure right under the thalamus
controls several metabolic functions, including body temperature, sexual arousal (libido), hunger, thirst, and the endocrine system.
limbic system
thalamus, hypothalamus, amygdala, and hippocampus
deal with aspects of emotion and memory
Hippocampus
two armlike structures surrounding the thalamus
vital to our memory system
Memories are processed through this area and then sent to other locations in the cerebral cortex for permanent storage
individuals with brain damage in this area are unable to retain new information
Amygdala
found at the end of each hippocampal arm
vital to our experiences of emotion
Cerebral Cortex
The gray, wrinkled surface of the brain
thin layer of densely packed neurons
pruning
When we are born, our cerebral cortex is full of neurons
As we develop and learn, the dendrites of the neurons in the cerebral cortex grow and connect with other neurons.
fissures
wrinkles increase the surface area contained within our skull
wrinkles
contralateral hemispheric organization
The idea that each side of the brain controls the opposite side of the body is called
current investigations into differences between hemispheres
the possibility that the left hemisphere may be more active during logic and sequential tasks and the right during spatial and creative tasks.
hemispheric specialisation
lateralisation
the specialization of function in each hemisphere