Studied by 0 people
Looks like no one added any tags here yet for you.
which pituitary gland is known as the adenohypophesis?
Ant. pituitary
Which pituitary gland is known as the neurohypophysis?
Post. lobe
Ant pituitary gland hormones:
Growth hormones (GH).
Prolactin (PRL).
Thyroid-stimulating hormone (TSH).
.Adrenocorticotropic hormone (ACTH).
Luteinizing hormone (LH).
Follicle-stimulating hormone (FSH).
All anterior pituitary hormones are tropic hormones except —
Prolactin
GH secreted → liver → ?
secrete IGF-1 → promotes growth of bone + soft tissue
Prolactin Inhibiting hormone is aka
Dopamine
How does GH ↑ glucose?
by inhibiting hexokinase in skeletal m.s & adipose tissue
↑ gluconeogenesis
↓ glucose utilization by cell
What are the half life of IGF-1 & GH?
GH: 20 minutes (short duration of action)
IGF-1: 20 hours (prolonged action)
Does GH increase glucose intake or decrease it?
Decrease ↓ glucose intake
(so it will accumulate in plasma)
What are the causes of pituitary dwarfism?
GHRH deficiency
GH deficiency
GH receptor insensitivity (Loran dwarfism)
IGF-1 deficient secretion by chondrocyte
Hereditary inability to form IGF-1 (Levi-Lorain dwarf)
Does pituitary dwarfism cause mental retardation?
No, only in thyroid dwarfism
How is the growth in pituitary dwarfism?
The growth is retarded and proportional so that span = hight
Vertex to symphysis = symphsis to heel.
thyroid dwarfism is aka?
Cretinism
GH deficiency in adults leads to:
percentage ratio of body weight protein is ?
Percentage ratio of body fats is ?
percentage ratio of body weight protein is ↓
Percentage ratio of body fats is ↑
How are the teeth in people with agromegaly?
they are separated bec. the jaw grows bigger but the teeth stay the same.
How is the vision of acromegally person?
bitemporal hemianopia
PIH is aka
Dopamine
ADH is formed by?
Supra-octic nuclei
Oxytocin is formed by?
Para ventricular nuclei
ADH effect of kidney
↑ permeability of late distal tubules & collecting duct → ↑ water + urea reabsorption
What receptor does ADH hold(?)
V1 ,V2 & V3 receptors
What receptor does ADH bind to cause vasoconstriction?
V1
Nicotine VS Alcohol effects n ADH
Nicotine: ↑ ADH
Alcohol: ↓ ADH
What happens to basal metabolic rate in diabetes insipidus?
↑ basal metabolic rate
Where is thyroglobulin formed?
in the follicular cell
Does the thyroid hormone move around freely?
No, it bounded to thyroid binding globulin(TBG) - Thyroid binding prealbumin(TBPA) - Albumin
Where in the cell is thyroid hormone receptors?
In the nucleus of the cell
Small doses of thyroid hormone are (anabolic - Catabolic)?
Anabolic
