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what is an aerosol
dispersion of a solid or liquid in a gas
what does a nebuliser do
converts a solution of a drug into an aerosol for inhalation
what are the different types of aerosols
MDI, nebliser or DPI
Metered dose inhaler facts (4)
most common
aerosol created when valve is opened
drug usually contained in small particles suspened in liquid propellant
nebuliser facts 2
oldest
uses drug contained in a solution
dry power inhaler facts 5
aerosol is a powder until inhaled
intended to be left in the device or in the mouth - throat
They add large particles of lactose monohydrate
how does a liquefied gas aerosol work 3
an equilibrium is established between the liquefied propellant and its vapour
when the valve is opened the pressure forces some liquid out of the dip tube and out into the atmosphere
aerosol propellant vaporises and disperse the active ingredient
liquified gas aerosol picture

what happens to vapour pressure in the liquefied gas aerosol
the vapour pressure therefore will remain constant
what do hydrofluroalkanes do (HFAs)
produce aerosols
whats a benefit of using HFAs over CFCs
HFAs do not destroy ozone layer
what are the two most common HFAs
tetrafluoroethane (HFA 134a) and heptafluoropropane (HFA 227)
what does a compressed gas aerosol contain
compressed gas and a solvent
what is the molar enthalpy of vaporisation
the quantity of heat absorbed when 1 mole of a liquid vaporises at the normal boiling point
In a compressed gas aerosol, indicate how the vapour pressure above the aerosol mixture will change during useage.
it will decrease
entonox gas is made up of what
50 : 50 mixture of nitrous oxide and oxygen
what is charles law
if the temperature increases then the volume increases proportionally.
what effect does increasing the temperature of a liquid have on its vapour pressure.
vapour pressure increases
Formulae you should know:
PTotal=POA XA +POB XB
P1V1= P2V2
(P1V1)/T1= (P2V2)/T2