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Levels of Organization
Arrangement from smallest to largest: Atom → Molecule → Organelle → Cell → Tissue → Organ → Organ System → Organism
Superior / Inferior
Above / Below
Anterior / Posterior
Front / Back
Medial / Lateral
Toward midline / Away from midline
Proximal / Distal
Closer to / Farther from point of attachment
Superficial / Deep
Closer to surface / Further inside the body
Cranial Cavity
Brain
Thoracic Cavity
Lungs, heart
Abdominal Cavity
Stomach, intestines, liver
Pelvic Cavity
Bladder, reproductive organs
Form Determines Function
Structure of body parts matches their jobs.
Protons
In nucleus, positive charge
Neutrons
In nucleus, no charge
Electrons
Orbit nucleus, negative charge
Ionic Bonds
Electrons transferred
Covalent Bonds
Electrons shared
Hydrogen Bonds
Weak attractions between polar molecules (e.g., water)
Water
Solvent, regulates temperature, involved in reactions
Oxygen
Needed for cellular respiration (ATP production)
CO₂
Waste product, regulates blood pH
Salts (electrolytes)
Conduct electrical impulses
Carbohydrates
Main energy source (glucose)
Lipids
Energy storage, cell membrane (phospholipids)
Proteins
Structure, enzymes, hormones, immune function
Nucleic Acids
DNA/RNA – store and transmit genetic information
Synthesis (Anabolism)
Builds molecules (e.g., protein synthesis)
Decomposition (Catabolism)
Breaks down molecules (e.g., digestion)
Exchange
Molecules trade parts (e.g., buffers in blood)
Nucleus
Stores DNA, controls cell
Mitochondria
Produces ATP (energy)
Ribosomes
Site of protein synthesis
Rough ER
Has ribosomes; processes proteins
Smooth ER
Lipid synthesis, detoxification
Golgi Apparatus
Packages and ships proteins
Lysosomes
Contain enzymes to digest cell waste
Cytoplasm
Gel-like fluid holding organelles
Prophase
Chromosomes condense, spindle fibers form
Metaphase
Chromosomes line up in the middle
Anaphase
Sister chromatids pulled apart
Telophase
Two new nuclei form
Cytokinesis
Cytoplasm splits into two cells
Phospholipid bilayer
Hydrophilic heads, hydrophobic tails
Proteins (in Membrane)
Transport, communication, support
Cholesterol
Stabilizes membrane
Carbohydrates (in Membrane)
Cell recognition
Simple diffusion
Small, nonpolar molecules
Facilitated diffusion
Uses protein channels
Osmosis
Diffusion of water
Endocytosis
Into the cell
Exocytosis
Out of the cell
Mediated Transport
Uses carrier proteins
Non-mediated Transport
Direct movement across membrane
Hypotonic solution
Cell swells
Hypertonic solution
Cell shrinks
Isotonic solution
Cell remains the same
Transcription
DNA → mRNA using RNA polymerase
Translation
mRNA → Protein using tRNA and ribosome
A–T, C–G
DNA base pairing
A–U, C–G
RNA base pairing
Epithelial Tissue
Covers body, lines organs (e.g., skin, intestines)
Connective Tissue
Supports/binds (e.g., bone, fat, blood)
Muscle Tissue
Movement (skeletal, cardiac, smooth)
Nervous Tissue
Sends electrical signals (brain, spinal cord)
Squamous (Epithelial Shape)
Flat
Cuboidal (Epithelial Shape)
Cube-shaped
Columnar (Epithelial Shape)
Tall
Simple (Epithelial Layers)
One layer
Stratified (Epithelial Layers)
Multiple layers
Simple squamous (Location & Function)
Lungs (gas exchange)
Stratified squamous (Location & Function)
Skin (protection)
Cartilage
Flexible, no blood supply, slower repair
Bone
Rigid, vascularized, strong
Mucous Membranes
Line cavities open to exterior (mouth, nose)
Serous Membranes
Line internal cavities (lungs, heart)
Cutaneous Membrane
Skin
Synovial Membranes
Line joint cavities, secrete fluid
Epidermis
Outer layer, no blood vessels, keratinized
Dermis
Connective tissue, blood vessels, nerves, glands
Subcutaneous (hypodermis)
Fat storage, insulation, energy
Sebaceous Glands
Oil production
Sweat Glands
Temperature regulation
Melanin
UV protection, pigment
Carotene
Yellow-orange pigment from diet
Hemoglobin
Red tint from blood
Long bones
Femur, humerus
Short bones
Carpals
Flat bones
Skull, ribs
Irregular bones
Vertebrae
Compact Bone
Dense, outer layer
Spongy Bone
Lighter, contains red marrow
Bone growth in length
At epiphyseal plate (growth plate)
Appositional growth
Adding layers
Resorption
Breakdown of bone by osteoclasts
Fibrous Joints
Immovable (e.g., skull sutures)
Cartilaginous Joints
Slightly movable (e.g., pubic symphysis)
Synovial Joints
Freely movable (e.g., knee, shoulder)
Synarthrosis
Immovable
Amphiarthrosis
Slight movement
Diarthrosis
Free movement
Flexion/Extension
Bending/straightening