Neurons, Glial Cells, and Brain Barriers (Intro to Neurobiology)

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Vocabulary flashcards covering key concepts from the lecture notes on neurons, glial cells, and the blood-brain barrier.

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15 Terms

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Neuron

Functional cell of the nervous system that generates and propagates electrical signals (action potentials) and secretes neurotransmitters.

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Glial cell

Supportive nervous system cell that insulates neurons, clears waste and excess neurotransmitter, and helps form barriers; roughly equal in number to neurons.

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Neuron doctrine

Idea that neurons are discrete, individual cells rather than a continuous net in the brain.

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Membrane potential

Voltage difference across a cell’s membrane; neurons change this during signaling.

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Resting membrane potential

Baseline membrane voltage of a neuron when it is not firing.

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Action potential

Rapid, self-propagating electrical signal that travels along a neuron to convey information.

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Excitable cell

Cell capable of changing its membrane potential in response to stimuli (e.g., neurons, muscle cells).

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Neurotransmitter

Chemical messenger produced by neurons and released to communicate with target cells.

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Neurotransmitter secretion

Release of neurotransmitters from neurons into the synapse or surrounding fluid.

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Myelination

Insulation of axons by glial cells to speed transmission and reduce current leakage.

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Astrocyte

A type of glial cell involved in regulating the brain environment and forming part of the blood-brain barrier.

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Blood-brain barrier

Selective barrier formed by brain capillaries and glial processes that blocks large molecules from entering brain tissue.

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Interstital fluid

Fluid surrounding brain cells in which neurotransmitters can diffuse.

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Brain cell populations

Two major populations: neurons (functional units) and glial cells (supportive helpers).

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Number of brain cells (concept)

Brain contains a large, roughly equal number of neurons and glial cells, each playing different roles in nervous system function.