Interphase

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5 Terms

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G1 (Gap1) Phase

  • very metabolically active

  • cell grows

  • produces rna and ribosomes needed for protein synthesis

  • produces new organelles

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S (Synthesis) Phase

  • DNA replication occurs

  • histones are produced so newly synthesized DNA molecules can be wrapped around them 

  • replication increases number of DNA molecules but NOT THE NUMBER OF CHROMSOMES

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G2 (Gap 2) Phase

  • mitochondria and chloroplasts replicate

  • more protein synthesis

  • Duplicated DNA is proofed and DNA damage is repaired

  • centrosomes and spindle fibers are formed

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Centrosomes

  • non membrane bound regions located near nucleus - mitotic center

  • initiate development of spindle fibres

  • in animal cells they are made up of centrioles arranged at right angles and responsible for orientating spindle fibres during division

  • centrosomes are made of microtubules

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Spindle Fibres

  • colchicine is used to arrest inhibit spindle formation arresting cells in metaphase stage

  • made of microtubules

  • form during mitosis and meiosis by centromere