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Screening for AAA
Men 65-75 who have ever smoked (A)
Test used to screen for AAA
Abdominal duplex ultrasonography
Treatment for AAA
>5.5 cm --> surgery
3.0-5.4 cm --> repeated surveillance Q3-12 months
Growth >1.0 cm/yr --> surgery
Screening for Alcohol Misuse
Persons older than 18 years
Screening Tests for Alcohol Misuse
AUDIT, AUDIT-C, or number of times person drank >5 (4 if woman or older than 65) drinks in the past year
Treatment for Alcohol Misuse
Behavioral Counseling interventions
Recommendation for Aspirin Usage
Men 45-79 years old (MI protection)
Women 55-79 (Stroke protection)
*Benefit of MI reduction must outweigh the risk of GI hemorrhage
Risk Factors For GI Hemorrhage
Men
Other NSAID usage
Hx of GI ulcer
Uncontrolled HTN
Anticoagulation
Screening for Asymptomatic Bacteriuria
Women at 12-16 weeks of pregnancy or first prenatal visit if farther along
Screening Test for Asymptomatic Bacteriuria
Urine culture
Dipstick and microscopy have poor PPV and NPV
Treatment for Asymptomatic Bacteriuria
Nitrofurantoin
Prophylactic Aspirin for the Prevention of Colon Cancer
The USPSTF DOES NOT recommend this due to risk of GI hemorrhage
Bacterial Vaginosis Screening in Pregnant Women
The USPSTF DOES NOT recommend this due to lack of evidence that it reduces mortality or morbidity
Amsel Criteria
Need 3/4:
1. Fishy odor with addition of KOH
2. Vaginal pH >4.7
3. Clue cells on wet mount
4. Thin, homogenous discharge
Treatment of BV
Oral Metronidazole or oral Clindamycin
or
Vaginal Metronidazole or Vaginal Clindamycin creams
Screening for Bladder Cancer
The USPSTF DOES NOT recommend this due to lack of accurate screening methods
Screening for HTN
Adults > 18 years
Diagnosis of HTN
>140 systolic or >90 diastolic
Must have 2 different BP readings that are elevated over a period of 1-several weeks
Categories of BP
Normal = <120/<80
PreHTN = 120-129/80-89
Stage 1 HTN = 140-159/90-99
Stage 2 HTN = 160+/100+
Major CV Risk Factors
HTN
Obesity
Dyslipidemia
DM
Cigarette smoking
Inactivity
Age >55 (men) or >65 (women
Family History of premature CVD: <55 (men) and <65 (women)
Causes of HTN
Sleep Apnea
Drug-induced (diuretics, cyclosporine, glucocorticoids, amiodarone)
Chronic kidney disease
Primary Aldosteronism (Conn's Syndrome)
Cushing's Syndrome
Pheochromocytoma (MEN II and III)
Coarctation of aorta (Turner's)
Thyroid/Parathyroid disease
Goal BPs for Treatment (JNC8)
<140/90 for adults <60 years without CKD
<150/90 for adults >60 years without CKD
<140/90 for all ages with DM, but no CKD
<140/90 for all ages with CKD +/- DM
Treatment of HTN for Non-Black without CKD
Thiazide Diuretic
ACE-I
ARB
CCB
Treatment of HTN for Black without CKD
Thiazide Diuretic
CCB
Treatment of HTN for All Races with CKD +/- DM
ACE-I
ARB
BRCA-Related Cancer Screening
All women with family members who had breast, ovarian, tubal, and/or peritoneal cancers
Medications for Breast Cancer Risk Reduction
Offer tamoxifen or raloxifene to women at high risk with low risk for adverse side effects
Mammography Screening
Women 50-74: biennial (every other year)
Women under 50: Take the patient's factors into context and weigh benefits and risks
Women >75: not recommended to get screening
Breastfeeding recommendations
Interventions to educate and encourage women during pregnancy and postnatal period to breastfeed
Carotid Artery Stenosis Screening
USPSTF DOES NOT recommend screening for the general population for asymptomatic carotid stenosis
Diagnostic Test for Carotid Artery Stenosis
Ultrasonography of Carotid Artery with Doppler flow
High Intensity Statin
Lowers LDL-C by >/=50%
Atorvostatin 40-80 mg
Rosuvostatin 20-40 mg
Medium Intensity Statin
Lowers LDL-C by 30-50%
Atorvostatin 10-20 mg
Rosuvostatin 5-10 mg
Simvastatin 20-40 mg
Provastatin 40-80 mg
Lovastatin 40 mg
Fluvastatin 40 mg BID
Low Intensity Statin
Lowers LDL-C by
Cervical Cancer Screening
Women 21-65 Pap smear with cytology Q3 years
Women 30-65 Pap smear with HPV testing Q5 years
Cervical Cancer Screening Exemptions
Women >65 years with previously normal screenings
Women who had a hysterectomy with removal of the cervix and no history of precancerous lesion
High Grade Intraepithelial Lesion Treatments
Cryotherapy, laser therapy, loop excision and cold knife excision
Early Stage Cervical Cancer Treatment
Surgery or chemoradiation
Ottawa Rules for Ankle
XR required if 1/3:
Tenderness at posterior edge of lateral malleolus
Tenderness at posterior edge of medial malleolus
Inability to bear weight both immediately after injury or in the ED
Ottawa Rules for Foot
XR required if 1/3:
Tenderness at base of 5th metatarsal
Tenderness at navicular
Inability to bear weight both immediately after injury or in the ED
Exceptions to the Ottawa Rules
Inebriation/uncooperative patient
Other distracting painful injuries that cloud the perception of pain in the regions listed in rules
Diminished sensation in legs
Gross swelling which prevents palpating of medial malleolus
**Patient is under 18 years old***
Ottawa Rules for Knee
Age >55
Isolated tenderness of patella
Tenderness at head of fibula
Inability to flex 90 degrees
Inability to bear weight both immediately and in the ED
Chlamydia and Gonorrhea Screening for Women
Women <24 who are sexually active
Women >24 with risk factors identified
Risk Factors for Gonorrhea/Chlamydial Infection in Women
Age 20-24
New sex partner
More than 1 sex partner
Sex partner with concurrent sex partners
Sex partner with an STI
Inconsistent condom usage
Previous or coexisting STI
Exchange of sex for money or drugs
Incarceration
Military recruits
Black and Hispanic
Screening Test for Gonorrhea/Chlamydia
Nucleic Acid Amplification Test (NAAT)
Screening for Chronic Kidney Disease
USPSTF has insufficient information to recommend screening for CKD in asymptomatic adults
Screening for COPD
The USPSTF DOES NOT recommend screening for COPD in asymptomatic adults using spirometry
Diagnosis of COPD
FEV1:FVC ratio of <70% with less than 12% reversibility
Colorectal Cancer Screening
Start screening at 50 years and continue until the age of 75 years
Screening Tests for Colorectal Cancer
Fecal Occult Blood Testing (annually)
Sigmoidoscopy (Q5 years)
Screening Colonoscopy (Q10 years)
Screening for Colon Cancer in Adults >75 years
76-85: recommendation against screening unless patient has risk factors
>85: do not screen as there is no net benefit
Screening for Congenital Hypothyroidism
All infants should be screened for T4 and TSH
Timing of Congenital Hypothyroidism Screening
Between 2-4 days of age
Treatment for Congenital Hypothyroidism
Confirmatory testing and thyroid hormone replacement within 2 weeks after birth
Dental Carries Prevention in Children Under 5 years
USPSTF recommends that fluoride should be prescribed for children 6 months to 5 years old if water is deficient in fluoride
Screening for Depression in Adults
Screen all adults 18+ when staff-assisted depression care supports are in place
Screening for Depression in Adolescents
Screen adolescents 12-18 years old for MDD when staff-assisted depression care supports are in place
Screening for DM Type 2 in Adults
Screen adults with sustained high blood pressure (treated or untreated) >135/80
Screening Tests for DM II
Fasting plasma glucose
2 hour post-load plasma glucose
HgbA1C
Fall Prevention in Older Adults
Exercise or physical therapy and Vit D supplementation to prevent falls in adults >65 years
Risk Factors for Falls
Age
Hx of falls
Hx of mobility problems
Poor performance on Get-Up-and-Go Test
Get-Up-and-Go Test
Time it takes for a person to rise from an armchair, walk 10 feet, turn, walk back and sit down
(Average healthy adult >60 years can do it in 10 seconds)
Folic Acid Supplementation in Pregnant Women
Take supplements with 0.4 to 0.8 mg of folic acid to reduce risk of NTDs
4.0 mg in women with a Hx of NTDs in prior pregnancies
**All women who are capable of pregnancy should take it**
Screening for HSV
USPSTF DOES NOT recommend screening asymptomatic pregnant women nor routine screening for asymptomatic adolescents and adults
Gestational Diabetes Mellitus Screening
Screen all pregnant women after 24 weeks of gestation
GDM Screening Test
50 g oral glucose challenge test (OGCT)
Positive OGCT?
(>130 mg/dL)
Do the 100 g oral glucose tolerance test (OGTT)
Interventions for Overweight/Obese Patients With Additional CVD Risk Factors
Behavioral counseling, with intense focus on healthful diet and physical activity, over an extended period of time
**Refer at a BMI of 30 + CVD risk factors**
Screening for Hearing Loss in Newborns
Screen all newborns
Screening Test for Newborns' Hearing
Otoaccoustic Emissions Test (OAE)
If failed OAE test, then follow up with Auditory Brainstem Response (ABR)
When to Screen Newborns for Hearing Loss
Before 1 month of age
Confirmatory testing before 3 months of age if failed first test
Screening for Hearing Loss in Adults
USPSTF has insufficient evidence to determine the benefits of screening for hearing loss in asymptomatic adults over the age of 50
Screening for Hepatitis B in Pregnant Women
Screen all pregnant women
Screening Test for Hepatitis B in Pregnant Women
HBsAg detection, regardless of previous negative HBsAg results
Timing of Screening for HBV in Pregnant Women
At first prenatal visit
At hospital for birth in women with unknown status or continuing risk factors for HBV infection
Treatment for HBV infection of pregnant women
Infants should receive HBV vaccine and HBIG within 12 hours of birth
Screening for HBV Infection in General Population
Screen all person at high risk for infection
Risk Factors for HBV Infection
Country of origin
Lack of immunization in persons with parents from a country/region with high prevalence
HIV infection
Injection Drug Users
Household or sexual contacts of HBV-infected persons
Male homosexuals
Hemodialysis
Immunosuppressive therapy
Treatment for HBV
Pegylated Interferon-Alpha-2a
entecavir
Tenofovir
Screening for Hepatitis C Infection in General Population
Screen all persons at high risk for infection
Screen adults born between 1945 and 1965
Screening Test for HCV Infection
Anti-HCV antibody testing, with confirmatory PCR testing
Risk Factors for HCV Infection
Past/present injection drug use
Sex with an injection drug user
Blood transfusion before 1992
Long term hemodialysis
Born to HCV-infected mother
Incarceration
Treatment for HCV Infection
Pegylated Interferon
plus
Ribavirin for 48 weeks
Screening for HIV
Screen in adolescents and adults aged 15-65 years
Screen younger adolescents and older adults at increased risk
Screen all pregnant women for HIV
Risk Factors for HIV Infection
Male Homosexuals
Active Injection Drug Users
Exchanging Drugs for Sex or Money
Sexual contact with a known HIV-positive individual
Screening Tests for HIV
Rapid screening test (positive results requires work up)
Serum testing: ELISA, followed by confirmatory Western Blot Immunofluorescent assay
Hyperbilirubinemia Screening in Infants
USPSTF has insufficient evidence to recommend screening for hyperbilirubinemia
Screening for Idiopathic Scoliosis in Asymptomatic Adolescents
USPSTF DOES NOT recommend screening for idiopathic scoliosis in asymptomatic adolescents
Screening for Intimate Partner Violence
Screen women of childbearing age for intimate partner violence and provide or refer women who screen positive to intervention services
Screening for Abuse of Elderly and Vulnerable Adults
USPSTF has insufficient evidence to recommend screening
Screening Test for Intimate Partner Violence
HITS (Hurt, Insult, Threaten, or Scream)
Screening for Iron Deficiency Anemia
USPSTF has insufficient evidence to recommend screening asymptomatic infants 6-12 months for Iron Deficiency Anemia
Screen all asymptomatic pregnant women
Iron Supplementation Recommendations
Routine iron supplementation for children aged 6-12 months at increased risk of developing Iron Deficiency Anemia
Routine supplementation for pregnant women with Iron Deficiency Anemia
Risk Factors for Developing Iron Deficiency Anemia
Rapid growth
Inadequate dietary intake
Blood loss
Decreased absorption
Prematurity
Screening For Lead Levels
USPSTF has insufficient evidence to recommend screening symptomatic children 1-5 years at increased risk
USPSTF DOES NOT recommend screening children 1-5 years with average risk
USPSTF DOES NOT recommend screening asymptomatic pregnant women
Screening for Lipid Disorders in Adults
Men >35: Screen them
Men 20-35: Screen if they have increased CVD risk
Women 20+: Screen them if they have increased CVD risk
Screening Test for Lipid Disorders
Lipid Panel: Total Cholesterol, LDL-C, HDL-C, Triglycerides
Screening for Lipid Disorders in Children 1-20
USPSTF has insufficient evidence to recommend screening children aged 1-20
Prophylactic Use of Aspirin in Pregnant Women
Low dose aspirin (81 mg) after 12 weeks in women at high risk for preeclampsia
Risk Factors for Preeclampsia
Hx of Preeclampsia
Multifetal gestation
Chronic HTN
DM
Renal disease
Autoimmune disease