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Sickle cell anemia
An autosomal recessive disorder
A chondrosarcoma is a:
A malignant tumor of cartilage
Dysplasia
An alteration in the size, shape, and organization of adult cells, usually due to an irritant
Exudate
A byproduct of inflammation that is composed of fluid, cells, and cellular debris that escapes the vessels and is deposited in the tissues
Capillary dilation
Begins the process of inflammation
All of the following are examples of additive diseases, except: ascites, pneumonia, hemorrhage, or osteoporosis
Osteoporosis
Characteristics of malignant tumors
Rapid growth and ability to metastasize
What type of disease of the immune system results in the body becoming allergic to itself?
Autoimmune diseases
True or false: Additive diseases are those that absorb more x-rays than normal tissues
True
Thrombus
A fixed blood clot that develops on a vessel wall that can obstruct blood flow
Homozygous
When a trait of an offspring is inherited as a dominant allele from both parents
Incidence
Measure of disease process reports the number of newly diagnosed cases in a particular time period
What are causes of DNA mutations?
Radiation, viruses, or spontaneous
Embolus
A blood clot that is carried along by the bloodstream to lodge in a distant site
Inflammation
The body’s common response to many different causative agents, such as infections and trauma
How is natural, passive immunity obtained?
Through breast milk or maternal blood
Atrophy
A reduction in the size or number of cells in an organ or tissue, with a corresponding decrease in function
Adenoma
A benign tumor of a gland
Immunodeficiency diseases
A disease of the immune system that results in the body becoming prone to opportunistic infections that would not cause serious illness in a healthy person
What is the purpose of inflammation?
To prepare the body for healing and repair
What are the signs and symptoms of inflammation?
Calor, rubor, and tumor
Diseases caused by the body’s inability to process nutrients needed to carry out functions
Metabolic diseases
Cells of benign tumors similar to normal cells
Differentiated
Petechia
A very small hemorrhage
Heterozygous
When a trait of an offspring is inherited as a dominant from one parent and a recessive from another
Pathology
the specialized branch of medicine that focuses on the study of disease, including the origin, nature, and structural and functional changes caused by disease
How is natural, active immunity acquired?
Through exposure to disease
What do vaccines provide?
Acquired, active immunity
All of the following are examples of autosomal dominant hereditary diseases, except: Huntington disease, Marfan syndrome, Tay-Sachs disease, or achrondroplasia
Tay-Sachs disease
What is the function of leukocytes in the process of inflammation?
Remove dead cells
Purpura
A hemorrhage of up to 1cm in size
Mortality rate
The number of deaths due to a particular disease in a given time frame
True or false: hereditary diseases can only be passed to offspring if both parents possess the defective gene
True
Hematoma
The medical term for a bruise
Hypertrophy
An increase in cell size in response to an increase in workload
All of the following are signs and symptoms of inflammation, except: pain, swelling, paralysis, or redness
Paralysis
The broad pathology classification systems
Causative agents and body system
What would be an appropriate technique adjustment to make when imaging a patient with known osteoporosis?
Decrease the kVp
Idiopathic
The term that describes diseases of unknown etiology
True or false: when imaging a patient with a destructive disease, the exposure factors should be decreased
True
Immunodeficiency disorders
Diseases that attack the natural immune system of the body and create a lack of resistance to other microorganisms
What is the appropriate technique adjustment when imaging a patient with a known pleural effusion?
Increase the kVp
Congenital
Diseases that are present at birth
What does not cause an infarct?
Ecchymosis
Endogenous
Diseases caused by an internal agent
Hangman’s fracture
A fracture of the arch of C2 anterior to the inferior facet usually associated with anterior subluxation or C2 and C3
An inherited disorder of connective tissue characterized by multiple fractures
Osteogenesis imperfecta
An expansile lucent lesion demonstrating a sharp demarcation from normal adjacent bone having a thin sclerotic rim
Unicameral cyst
A true osteochondroma grows laterally from the epiphysis and must exhibit:
A cortex and medullary portion
A tumor growing parallel to the bone and points away from the adjacent joint
Osteochondroma
Growth of outer bone diameter is dependent upon which bone cell?
Osteoblasts
To assess bone mineral content from a qualitative approach, the best imaging modality is:
Dual-energy x-ray absorptiometry (DEXA)
Herniation of the meninges in the lumbar or cervical vertebra
Meningocele
A fracture resulting from a weakness in the bone caused by a tumor or infection
Pathologic fracture
The bone lesion typically seen as a small (less than 1cm) round area with a lucent center
Osteoid osteoma
Bone that develops within the connective tissue
Intramembranous ossification
In Paget’s disease, the beginning phase involves bone _____
Destruction
A cyst-like lesion causing ballooning and possibly having internal septations
Aneurysmal bone cyst
The most common form of dwarfism caused by decreased enchondral bone formation
Achondroplasia
A fracture usually caused by falling on an outstretched hand resulting in posterior displacement of the distal fragment of the radius
Colles’ fracture
A classic sunburst pattern of bony spicules that extend in a radiating fashion is a radiographic appearance of:
Osteogenic sarcomas
The hollow, tube-like structure within the diaphysis
Medullary cavity
Malunion
Healing of fracture fragments in a faulty position
Body weight on weight-bearing bones may bend or bow as a result of softened bones in cases of:
Osteomalacia
Complete fracture
Discontinuity of two or more fragments
Transitional vertebra
A vertebra with characteristics of more than one major division of the spine
Osteoarthritis
The most common form of degenerative arthritis that has osteophyte development
To demonstrate degenerative knee joint narrowing most accurately requires the image to be:
Weight bearing standing AP and lateral
Lobulated borders from endosteal scalloping containing focal areas of high signal intensity on T2 weighted MRI images is suggestive of an:
Enchondroma
A weblike arrangement of marrow-filled spaces separated by thin bone
Cancellous bone
The disorder in which the disease process begins as an inflammation of the synovial membrane causing synovial proliferation
Rheumatoid arthritis
The fluid-filled sac located near joints becomes inflamed, which results in:
Bursitis
The modality that best demonstrates early changes in osteomyelitis
MRI
The secondary ossification center in a long bone
Epiphysis
Malignant bone lesions cause soft-tissue swelling and:
Cortical bone erosion, causing a poorly defined margin
The classic radiographic appearance of multiple punched-out osteolytic lesions scattered throughout the skeletal system is suggestive of:
Multiple myeloma
A rare hereditary bone dysplasia involving the bone resorption mechanism of calcified cartilage
Osteoporosis
Proliferation of fibrous tissue in the medullary cavity
Fibrous dysplasia
When a pyogenic organism enters the joint through the blood, direct extension, or trauma
Infectious arthritis
Primary malignant tumors arising from the bone marrow of long bones in children and young adults, usually causing localized pain
Ewing’s sarcoma
The most common initial site of Paget’s disease
Pelvis
A disease process usually caused by accelerated bone resportion
Osteoporosis
Osteoclastic cell
A cell associated with bone resorption and bone removal
Suspected non-accidental trauma of children
Battered-child syndrome
Which modality best demonstrates menisci tears?
MRI
An insufficient mineralization of the adult skeleton appearing as a loss of bone density
Osteomalacia
Which modality best demonstrates rotator cuff tears?
MRI
For brittle bone disease, the radiographer should _____ (increase, decrease) technique factors
Decrease kVp
The modality that best detects asymptomatic bone metastases
Radionuclide bone scan
Forward displacement of one vertebra on the other, resulting in back pain caused by cleft in the pars interarticularis
Spondylolisthesis
Osteomyelitis is characterized by the result of:
Bacteria, pyogenic, or postoperative complications
Disease characterized as blood levels with an increased uric acid leading to deposits of crystals in the joints and cartilage
Gout
Periosteum
A fibrous membrane that covers the outer bone
A pattern of lytic and sclerotic new bone growth with a flattening of the femoral head associated with periosteal new bone
Ischemic necrosis
The disorder that begins as a bone abscess that travels through the medullary cavity and outward to lift the periosteum
Osteomyelitis
The study of the cause of disease
Etiology
Diseases that result from an abnormal cellular proliferation and function
Neoplastic
Stenosis
A narrowed region of a vessel that can cause ischemia
How would the pathology evident be categorized?
Destructive
The predicted course of a disease, including the probable outcomes
Prognosis