FPS Exam 4 Excipients

Poloxamers (Pluronics)

- Nonionic Surfactants

- Emulsifying agent

Spans (sorbitan esters)

- Nonionic Surfactant

- W/O Emulsifying agent

Tweens (polysorbate)

- Nonionic Surfactant

- O/W Emulsifying agent

Cetrimide (CTAB)

Cationic surfactant

Sodium Lauryl Sulfate (SLS)

- Anionic surfactant

- Emulsifying agent

Methylcellulose

- Polymer

- Increase viscosity

- Emulsion by produced film

Carboxymethylcellulose

- Polymer

- Increase viscosity

- Emulsion by produced film

Carbomer

- Polymer

- Increase viscosity

- Emulsion by produced film

Hydroxypropylcellulose

Polymer - Increase viscosity

Xanthan gum

Polymer - Increase viscosity

Magnesium aluminum silicate (Veegum)

- Clay

- Increase viscosity

- Stabilizer

Bentonite

- Clay

- Increase viscosity

- O/W and W/O Emulsifier by swelling in water

Kaolin

- Clay

- Increase viscosity

Acacia/Guar Gum

- Natural hydrocolloid

- Increase viscosity

- O/W Emulsion by produced film

Tragacanth

- Natural hydrocolloid

- Increase viscosity

- Emulsion by produced film

Agar

- Natural hydrocolloid

- Increase viscosity

- Emulsion by produced film

Pectin

- Natural hydrocolloid

- Increase viscosity

- Emulsion by produced film

Propylene Glycol

Increase viscosity

Citrate

Buffer

Phosphate

Buffer

Acetate

buffer

Sucrose

- Organoleptic Sweetener

- Tonicity

Sorbitol

Organoleptic Sweetener

Saccharin

Organoleptic Sweetener

Aspartame

Organoleptic Sweetener

Parahydroxy Benzoic Acids

Antimicrobial preservative

Benzoic acid/Sodium benzoate

Antimicrobial preservative

Sorbic acid

Antimicrobial preservative

Histidine

Buffer

Succinate

Buffer

Sodium Chloride

- Tonicity

- Viscosity reducing

Trehalose

Tonicity

Arginine

Viscosity reducing

Glycine

Viscosity reducing

Glycerin

- Tonicity

- Wetting agent

Alcohol

Wetting agent

Sodium Stearate

- Anionic Surfactant

- Emulsifying agent

Triethanolamine Stearate

- Anionic Surfactant

- Emulsifying agent

Calcium Stearate

- Anionic Surfactant

- Emulsifying agent

Cetrimide

- Cationic Surfactant

- Weak Emulsifying agent

- Antibacterial

Benzalkonium chloride

- Cationic Surfactant

- Weak Emulsifying agent

- Antibacterial

Cetylpyridinium Chloride

- Cationic Surfactant

- Weak Emulsifying agent

- Antibacterial

Cholesterol in combination

- Nonionic

- Emulsify/ Stabilize

Oleyl Alcohol

- O/W Emulsifier

- Stabilize

Cetyl Alcohol

- O/W Emulsifier by forming gel structure

- Stabilize

Sodium Cetyl Sulphate

- Anionic Surfactant

- O/W Emulsifier

- Stabilize

Gelatin

- O/W Emulsion by produced film

Glyceryl Monostearate

- Increase viscosity

- Auxiliary Emulsifier by forming gel structure

Cetostearyl Alcohol

- Increase viscosity

- Auxiliary Emulsifier by forming gel structure

Stearic Acid

- Increase viscosity

- Auxiliary Emulsifier by forming gel structure

Egg Yolk Phospholipids

- Natural Emulsifying agent

Disodium EDTA

- Antimicrobial

- Chelating agent